Results 91 to 100 of about 905,382 (336)

The Effectiveness of Oxandrolone in Promoting Linear Growth in Growth Hormone Deficient Children [PDF]

, 1973
This two-year study consisted of a comparison of oxandrolone and growth hormone for the treatment of five children with documented growth hormone deficiency.
Mellinger, Raymond C., Morrow, Lewis B., Saeed-uz Zafar, M., Wolf, Charles B.   +3 more
core   +1 more source

Is Growth Hormone the Fountain of Youth? [PDF]

, 2023
Finding the cure for aging has been a sought-after quest for as long as the world has existed. Growth hormone has been shown as a possible treatment to negate the phenotypic effects of aging.
David Youlus
core   +1 more source

Murine Models and Human Cell Line Models to Study Altered Dynamics of Ovarian Follicles in Polycystic Ovary Syndrome

Advanced Biology, EarlyView.
The manuscript examines preclinical murine and human models to study polycystic ovary syndrome (PCOS), delving into the cellular and molecular mechanisms underlying altered ovarian follicular dynamics. It explores the cellular interactions involved in normal and PCOS ovaries and outlines the current and novel strategies in the search for preclinical ...
Arturo Bevilacqua, Cristiano Giuliani, Giovanna Di Emidio, Samuel H Myers, Vittorio Unfer, Carla Tatone   +5 more
wiley   +1 more source

Growth Hormone Deficiency

Güncel Pediatri, 2010
Growth hormone deficiency is the most promising entity in terms of response to therapy among the treatable causes of growth retardation. It may be due to genetic or acquired causes.
Ömer Tarım, Halil Sağlam
doaj  

Isolated Growth Hormone Deficiency

Endocrines
Growth hormone deficiency (GHD) is the most frequent pituitary hormone deficiency in childhood, with an incidence of 1 in 4000–10,000 live births. GHD can be congenital (genetic or due to hypothalamic/pituitary abnormalities) or acquired and can be ...
Anastasia Ibba, Chiara Guzzetti, Lavinia Sanfilippo, Sandro Loche   +3 more
doaj   +1 more source

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

Advanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan, Simona Summonte, Fabrizio Ricci, Matthias Sandmeier, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source

Characterisation of modified pharmaceutical proteins: the somatropin case [PDF]

, 2010
Somatropin, a recombinant protein containing 191 amino acids, is derived from the endogenous human growth hormone, somatotropin [1]. This protein is clinically used in children and adults with inadequate endogenous growth hormone to stimulate a normal ...
De Spiegeleer, Bart, Wiskerke, Daphne, Wynendaele, Evelien   +2 more
core  

Primary growth hormone insensitivity (Laron syndrome) and acquired hypothyroidism: a case report [PDF]

, 2011
Introduction Primary growth hormone resistance or growth hormone insensitivity syndrome, also known as Laron syndrome, is a hereditary disease caused by deletions or different types of mutations in the growth hormone receptor gene or by post-receptor ...
AL Rosenbloom, B Klinger, F Lupu, Francesco Trimarchi, Gianluca Aimaretti, Ginevra Corneli, I Ben-Dov, L Fassone, Libero Santarpia, Lorenzo Curtò, M Scheinowitz, MA Berg, MO Savage, Oana R Cotta, R Eshet, Salvatore Cannavò, SD Chernausek, Z Laron, Z Laron, Z Laron, Z Laron, Z Laron   +21 more
core   +3 more sources

Concentration of Growth Hormone and Fruitfulness in the Montmorency Cherry [PDF]

, 1942
Felix G. Gustafson
openalex   +1 more source

3D Bioprinted Coaxial Testis Model Using Human Induced Pluripotent Stem Cells:A Step Toward Bicompartmental Cytoarchitecture and Functionalization

Advanced Healthcare Materials, EarlyView.
The ability of human induced pluripotent stem cells (hiPSCs) to model developmental processes makes them a promising source for engineering testicular tissues to study in vitro maturation and sperm production. This work describes the first hiPSC‐derived testicular model and shows that it captures functional aspects of prepubertal testicular tissues ...
Meghan A Robinson, Sonia HY Kung, Khaled YM Youssef, Kali M Scheck, Robert H Bell, Funda Sar, Anne M Haegert, M Mahdi Asmae, Changfeng Cheng, Salina V Yeack, Bhairvi T Mathur, Feng Jiang, Colin C Collins, Faraz Hach, Stephanie M Willerth, Ryan K Flannigan   +15 more
wiley   +1 more source