Results 71 to 80 of about 600,427 (260)

Early cessation and non-response are important and possibly related problems in growth hormone therapy: An OZGROW analysis

, 2016
Objective: To investigate growth hormone (GH) treatment and treatment cessation with respect to efficacy and efficiency. To identify factors that best classify or predict cessation type: completed treatment (CT), early cessation (EC), or non-response (NR)
Harris, M., Cutfield, W., Cotterill, A, Hughes, IP, Hughes, I., Harris, M, Rath, S, Cutfield, Wayne, Choong, C., Cotterill, A., Rath, S., Choong, C, Hofman, Paul, Atkinson, Helen, Hofman, P., Atkinson, H   +15 more
core   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang, Dongxu Zhang, Dongyuan Liu, Da Lin, Hao Wang   +4 more
wiley   +1 more source

Growth hormone and heart failure: Oxidative stress and energetic metabolism in rats

, 2008
Several evidences point for beneficial effects of growth hormone (GH) in heart failure (HF). Taking into account that HF is related with changes in myocardial oxidative stress and in energy generation from metabolic pathways, it is important to clarify ...
Padovani, Carlos Roberto, Novelli, E. L. B., Okoshi, Katashi [UNESP], Nascimento, A. [UNESP], Castro, A. V. B., Nascimento, A., Ebaid, Geovana Xavier, Ebaid, Geovana Xavier [UNESP], Padovani, Carlos Roberto [UNESP], Cicogna, Antonio Carlos [UNESP], Seiva, F. R. F., Rocha, K. K. H. [UNESP], Seiva, F. R. F. [UNESP], Castro, A. V. B. [UNESP], Okoshi, Katashi, Cicogna, Antonio Carlos, Novelli, E. L. B. [UNESP], Rocha, K. K. H.   +17 more
core   +1 more source

Sex Differences in Medication Discontinuation in Axial Spondyloarthritis

Arthritis Care &Research, EarlyView.
Objective We examined sex differences in medication discontinuation among patients with axial spondyloarthritis (axSpA) initiating tumor necrosis factor inhibitors (TNFi), interleukin‐17 inhibitors (IL‐17i), or JAK inhibitors (JAKi). Methods Using data from the Rheumatology Informatics System for Effectiveness (RISE) Registry (2003–2025), we assessed ...
Rachael Stovall, Cinthia Blat, Eric Roberts, Jean W. Liew, Katherine Wysham, Namrata Singh, Janna Friedly, Lianne S. Gensler, Gabriela Schmajuk, Jinoos Yazdany   +9 more
wiley   +1 more source

Growth hormone (GH)-releasing hormone and GH secretagogues in normal aging: Fountain of Youth or Pool of Tantalus?

, 2008
Elizabeth C Hersch, George R MerriamVA Puget Sound Health Care System and University of Washington School of Medicine, Tacoma and Seattle, Washington USAAbstract: Although growth hormone (GH) is primarily associated with linear growth in childhood, it ...
Elizabeth C Hersch, George R Merriam
core  

Association Between Symptomatic Knee Osteoarthritis and Target Glycemic Control in Individuals With Type 2 Diabetes

Arthritis Care &Research, EarlyView.
Objective Knee osteoarthritis (OA) commonly affects individuals with type 2 diabetes (T2DM) and is associated with increased risk of diabetes‐related complications. To better understand potential mechanisms, we examined the association between symptomatic knee OA and glycemic control in individuals with T2DM.
Lauren K. King, Alanna Weisman, Baiju R. Shah, Robert Goldberg, Amish Parikh, Ian Stanaitis, Vivian Hung, Rosane Nisenbaum, Abdalmohsen Almodahka, Lorraine Lipscombe, Gillian A. Hawker   +10 more
wiley   +1 more source

Rheumatologic Manifestations of Patients With Type B Insulin Resistance

Arthritis Care &Research, EarlyView.
Objective The objectives of this study were to identify laboratory and clinical features associated with type B insulin resistance (TBIR), a rare condition caused by autoantibodies that inhibit the insulin receptor, most frequently occurring in the setting of systemic lupus erythematosus (SLE), and to increase awareness of this rare, life‐threatening ...
S. Amara Ogbonnaya, Sandra G. Williams, Raphael A. Kirou, Marissa Lightbourne, Rebecca J. Brown   +4 more
wiley   +1 more source

Thermogenic activity of growth hormone transgenic mice

, 1998
The objective was to determine the effect of a mouse metallothionein/bovine growth hormone transgene on resting metabolic rate (RMR), cold-induced thermogenesis, and beta-agonist stimulated nonshivering thermogenesis in mice.
Lamberson, W. R., Spiers, D. E., Moura, ASAMT   +2 more
core   +1 more source

A comparison of different definitions of growth response in short prepubertal children treated with growth hormone

, 2011
How to define poor growth response in the management of short growth hormone (GH)-treated children is controversial.
Tapanainen, P,, Bang, Peter,, P. Bang, Bjerknes, R., Dahlgren, J, Gustafsson, J, Bjerknes, R,, Dunkel, L,, Dunkel, L., V. Åberg, J. Gustafsson, Bang, P., Aberg, V, Bang, P,, Bang, P, Tapanainen, P., Juul, A, Kriström, Berit,, R. Bjerknes, Bjerknes, R, Gustafsson, J,, Dahlgren, J., Dahlgren, J,, Kriström, B, Kriström, B., Gustafsson, Jan,, L. Dunkel, A. Juul, Kriström, B,, Tapanainen, P, J. Dahlgren, Åberg, V., B. Kriström, P. Tapanainen, Juul, A,, Åberg, V,, Juul, A., Dunkel, L   +37 more
core   +1 more source