Results 191 to 200 of about 509,115 (292)

The Nuclear Localization of ACLY Guards Early Embryo Development Through Recruiting P300 and HAT1 to Promote Histone Acetylation and Transcription

Advanced Science, EarlyView.
ACLY is vital for early embryo development. IGF‐1 activates AKT to phosphorylate ACLY, driving its nuclear localization and recruitment of HATs (P300/HAT1), boosting acetyl‐CoA production and histone acetylation for transcriptional activation. Conversely, ACLY deficiency (via knockdown, knockout, or AKT inhibition) reduces nuclear acetyl‐CoA, disrupts ...
Yerong Ma, Yingyi Zhang, Weijie Yang, Xiaomei Tong, Siya Liu, Yan Zhou, Mengjia Qiu, Huifang Jiang, Zhanhong Hu, Peipei Ren, Yan Rong, Mengru Lai, Jiamin Jin, Fei Huang, Liujian Ouyang, Feng Zhou, Heng‐Yu Fan, Yin‐Li Zhang, Songying Zhang   +18 more
wiley   +1 more source

Developing a Process for Preference Measures in Pediatric Growth Hormone Deficiency: Challenges and Solutions. [PDF]

Patient Prefer Adherence
Brod M, Pfeiffer KM, Alolga SL, Beck JF, Murphy M, Bruchey AK, Maniatis A, Pitukcheewanont P.   +7 more
europepmc   +1 more source

Serum Growth Hormone Levels and the Response of Diabetic Retinopathy to Pituitary Ablation [PDF]

, 1969
Alexander D. Wright, E M Kohner, N. W. Oakley, M. Hartog, G. F. Joplin, T. R. Fraser   +5 more
openalex   +1 more source

Hypoglycemia Induces Diabetic Macrovascular Endothelial Dysfunction via Endothelial Cell PANoptosis, Macrophage Polarization, and VSMC Fibrosis

Advanced Science, EarlyView.
This study investigates hypoglycemia‐induced diabetic macrovascular endothelial dysfunction. It reveals that hypoglycemia triggers ZBP1‐dependent PANoptosis of endothelial cells, proinflammatory polarization of macrophages, and fibrosis of vascular smooth muscle cells (VSMCs) in diabetic mice.
Deyu Zuo, Yuce Peng, Guozhi Zhao, Zhesheng Cheng, Minghao Luo, Dingyi Lv, Shuting Chang, Na Li, Yanyao Huang, Xunjia Li, An He   +10 more
wiley   +1 more source

Neonatal Symptoms in Pediatric Idiopathic Growth Hormone Deficiency: Prevalences and Insights. [PDF]

Children (Basel)
Sodero G, Rigante D, Cipolla C.
europepmc   +1 more source

THE ROLE ÔF GROWTH HORMONE IN THE MOBILIZATION OF FUEL FOR MUSCULAR EXERCISE [PDF]

, 1965
W. M. Hunter, Charith Fonseka, R. Passmore   +2 more
openalex   +1 more source

Chronic Psychological Stress Induces Cardiomyocyte Hypertrophy Through Corticosterone‐Glucocorticoid Receptor‐LAMA5 Axis

Advanced Science, EarlyView.
In vivo experiments suggest that cardiomyocyte hypertrophy is an early manifestation of cardiac pathological changes induced by chronic psychological stress. In vivo and in vitro experiments suggest that the corticosterone‐glucocorticoid receptor‐LAMA5 axis mediates cardiomyocyte hypertrophy induced by chronic psychological stress. The clinical results
Chuanjing Zhang, Yongfei Song, Xiaojun Jin, Qingbo Xu, Honghua Ye, Zhuonan Wu, Hui Lin, Jiale Hu, Chen Huang, Jianqing Zhou, Jiangfang Lian   +10 more
wiley   +1 more source

Long-Acting Growth Hormone Therapy in Pediatric Growth Hormone Deficiency: A Consensus Statement.

J Clin Endocrinol Metab
Maniatis A, Cutfield W, Dattani M, Deal C, Collett-Solberg PF, Horikawa R, Maghnie M, Miller BS, Polak M, Sävendahl L, Woelfle J.   +10 more
europepmc   +1 more source

Nicotinic acetylcholine receptors regulate growth hormone in pituitary somatotrophs of tigers. [PDF]

Commun Biol
Liu L, Yang S, Chai L, Zhang S, Liu D, Xu H, Zhao Y, Chen S, Jiang G, Li B.   +9 more
europepmc   +1 more source

Growth Hormone Symposium

, 1954

openalex   +1 more source