Results 201 to 210 of about 5,571,602 (257)
Investigations of the Evolved Molecular Basis for Terpenoid Biosynthesis in Marine Sponges
Advanced Science, EarlyView.Confirming and extending a previous observation in another Bubarida sponge, genomic and functional analyses of A. cavernosa reveal that sponges retain the mevalonate pathway and employ single α‐domain T1TSs and UbiA‐type TSs for terpenoid biosynthesis. The absence of T1TSs clustering with other biosynthetic genes tentatively suggests, based on limited ...
Fangyan Chen +6 more
wiley +1 more source
Advanced Science, EarlyView.Disturbed flow promotes the formation of TRIM21‐rich biomolecular droplets, which concentrate TRIM21 and PTPN14 and facilitate their SPRY‐FERM interaction (illustrated by the TRIM21 D355‐PTPN14 R132 salt bridge). This condensate‐driven proximity enables TRIM21 to catalyze K48‐linked polyubiquitination of PTPN14 at lysine 956, leading to proteasome ...
Xue He +10 more
wiley +1 more source
Growth hormone-releasing hormone-treatment of growth-hormone deficient children
, 1986 Ross, R +7 more
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Pediatrics, 1965
Growth hormone influences protein, fat, carbohydrate, and mineral metabolism. It promotes nitrogen retention, growth of cartilage, transportation of amino acids through the cell wall, and incorporation of amino acids into protein. This factor mobilizes free fatty acids from adipose tissue and increases the serum concentration of these substances; long ...
F, MATSUZAKI, M S, RABEN
+7 more sources
Growth hormone influences protein, fat, carbohydrate, and mineral metabolism. It promotes nitrogen retention, growth of cartilage, transportation of amino acids through the cell wall, and incorporation of amino acids into protein. This factor mobilizes free fatty acids from adipose tissue and increases the serum concentration of these substances; long ...
F, MATSUZAKI, M S, RABEN
+7 more sources
Growth Hormone-Releasing Hormone*
Endocrine Reviews, 1986The identification of GRH has been followed by an extraordinarily rapid rate of knowledge accumulation. Within a period of slightly more than 3 yr since the structure of the GRH was determined, nearly 500 papers have been published pertaining to the hormone. Extensive knowledge of its anatomy, chemistry, molecular biology, physiology, and pathology has
L A, Frohman, J O, Jansson
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2009
Human growth hormone (hGH) is a proteohormone secreted by the pituitary gland. It acts through binding to the hGH receptor, inducing either direct effects or initiating the production of insulin-like growth-factor I (IGF-I), the most important mediator of hGH effects.
Martin, Bidlingmaier +1 more
openaire +2 more sources
Human growth hormone (hGH) is a proteohormone secreted by the pituitary gland. It acts through binding to the hGH receptor, inducing either direct effects or initiating the production of insulin-like growth-factor I (IGF-I), the most important mediator of hGH effects.
Martin, Bidlingmaier +1 more
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Dosing of Growth Hormone in Growth Hormone Deficiency
Hormone Research in Paediatrics, 1999Growth hormone (GH) treatment of GH-deficient (GHD) children is to a certain extent standardized worldwide. Recombinant 22 kDa GH is injected once daily by the subcutaneous route, mostly in the evening. The amount of GH injected (calculated per kg body weight or body surface area, expressed in terms of IU or mg) in prepubertal children mimics the known
M B, Ranke +3 more
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Mineral and Electrolyte Metabolism, 1994
Until a few years ago, growth hormone (GH) and insulin-like growth factor-1 (IGF-1) were considered essential only to the control of linear growth, glucose homeostasis, and for the maintenance of skeletal muscle mass. A large body of evidence recently coming from animal and human studies has unequivocally proven that the heart is a target organ for the
CITTADINI, ANTONIO +3 more
openaire +8 more sources
Until a few years ago, growth hormone (GH) and insulin-like growth factor-1 (IGF-1) were considered essential only to the control of linear growth, glucose homeostasis, and for the maintenance of skeletal muscle mass. A large body of evidence recently coming from animal and human studies has unequivocally proven that the heart is a target organ for the
CITTADINI, ANTONIO +3 more
openaire +8 more sources
Pediatrics, 1966
THE RECENT cascade of knowledge of the chemistry and physiology of the protein and polypeptide hormones of the pituitary gland has been a consequence of steady progress over the past 20 years in methods of isolation, purification, and assay of these hormones.
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THE RECENT cascade of knowledge of the chemistry and physiology of the protein and polypeptide hormones of the pituitary gland has been a consequence of steady progress over the past 20 years in methods of isolation, purification, and assay of these hormones.
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European Journal of Pediatrics, 1989
Seven children with growth hormone deficiency of hypothalamic origin responded to an i.v. bolus of growth hormone releasing hormone (GHRH) (1-29)-NH2 with a mean serum increase of 10.7 ng/ml growth hormone (GH) (range 2.5-29.3 ng/ml). Continuous s.c.
O, Butenandt, B, Staudt
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Seven children with growth hormone deficiency of hypothalamic origin responded to an i.v. bolus of growth hormone releasing hormone (GHRH) (1-29)-NH2 with a mean serum increase of 10.7 ng/ml growth hormone (GH) (range 2.5-29.3 ng/ml). Continuous s.c.
O, Butenandt, B, Staudt
openaire +2 more sources