Results 211 to 220 of about 5,829,861 (298)

ZBTB11 Promotes Breast Cancer Progression by Activating FBXO28‐Mediated MST1 Degradation and Suppressing Hippo Signaling

Advanced Science, EarlyView.
ZBTB11 is identified as an oncogenic transcription factor that activates FBXO28 in breast cancer. FBXO28 promotes K48‐linked ubiquitination and degradation of MST1, suppressing Hippo signaling and enhancing epithelial–mesenchymal transition and metastasis. This transcription‐to‐ubiquitination cascade defines a prognostic biomarker axis and highlights a
An Xu, Xiang‐Nan Xu, Xiao Huang, Zhou Luo, Chun‐Lian Li, Yang Du, Cheng Yan, Xiao‐Jie Yu, Jian‐Wen Wang, Long‐Di Yao, De‐Yuan Fu   +10 more
wiley   +1 more source

Diurnal and Daily Variations in Growth Hormone and Growth Hormone Stimulation Test in Male Cynomolgus Monkeys. [PDF]

In Vivo
Taniguchi Y, Yoshikawa T, Yamada T, Kawaguchi H.   +3 more
europepmc   +1 more source

SIZ1‐Mediated SUMOylation of LBD29 Recruits ARF7 to Fine‐Tune Auxin Signaling in Lateral Root Development

Advanced Science, EarlyView.
Our findings establish SUMOylation as a key post‐translational control layer in auxin signaling. We show that SIZ1‐mediated SUMOylation of LBD29 promotes its association with ARF7, stabilizing a transcriptional hub that governs lateral root development.
Jiaxuan Sui, Qianlan Yin, Yiying Chen, Liping Zhang, Xiuyuan Yu, Qianqian Yu, Zhaojun Ding, Xiangpei Kong   +7 more
wiley   +1 more source

Growth Hormone-Induced Stridor in a Patient With Prader-Willi Syndrome. [PDF]

Clin Case Rep
Saad AM, Zaki H, Menon A, Hausdorff M, Manzi B.   +4 more
europepmc   +1 more source

A Sustainable Bio‐Based Epoxy Thermoset as a High‐Performance Alternative to BPA‐Based Resins

Advanced Science, EarlyView.
A rigid–flexible bio‐based epoxy network integrates soybean oil, lignin, and maleic anhydride to overcome the strength–toughness–sustainability trade‐off of conventional BPA epoxy. The thermoset delivers excellent performance as both a structural adhesive and a matrix for glass‐fabric composites, while enabling pH‐responsive degradation, environmental ...
Jiyun Qi, Xinyi Hui, Xipeng Zhang, Jia‐Long Wen, Tong‐Qi Yuan   +4 more
wiley   +1 more source

Decoding growth hormone actions on human growth plate stem cells. [PDF]

Trends Endocrinol Metab
Orikasa S, Ono N.
europepmc   +1 more source

A Supramolecular Thermal Switch for Precision Pyroptosis via Host−Guest Recognition and Electrostatic Interactions

Advanced Science, EarlyView.
A supramolecular pyroptotic thermal switch encapsulates I3− within β‐cyclodextrin (β‐CD) and undergoes CaCO3 mineralization. Upon lysosomal acidification, CaCO3 is degraded, releasing Ca2+ and I3−. Concurrently, BODIPY activation converts I3− into I2, inducing oxidative stress and Ca2+ overload, which together trigger caspase‐3/GSDME‐mediated ...
Dan Wu, Jie Zhou, Yibin Cao, Kunmin Ping, Borui Zhao, Yanrong Yang, Chunyang Yu, Xinyang Yu, Shaolong Qi   +8 more
wiley   +1 more source

The relationship between pituitary size and the response to recombinant human growth hormone therapy in children with isolated growth hormone deficiency. [PDF]

Front Endocrinol (Lausanne)
Köprülü Ö, Coşkun M, Çelik E, Erbaş İM, Nalbantoğlu Ö, Korkmaz HA, Özkan B.   +6 more
europepmc   +1 more source

Transposable Element–Driven PIEZO Mutation Enhances Locust Flight in Plateau Hypoxia

Advanced Science, EarlyView.
Why transposable elements (TEs) persisted or expanded in genomes remains a mystery. Using integrated analysis of TE macro‐ and microevolution in locusts, our results showed that thousands of TE insertions promoted widespread adaptive variation. Subfamilies of candidate adaptive TEs amplified and reshaped species‐level genomic architecture.
Xuanzhao Li, Ying Liu, Longsheng Xing, Xianliang Huang, Yingming Sun, Lei Yue, Yuze Zhang, Huilong Du, Bing Chen   +8 more
wiley   +1 more source

Growth hormone-secreting adenoma with lack of retinoblastoma protein expression. [PDF]

JCEM Case Rep
Salvatori R, Gallia GL, Lucas CG.
europepmc   +1 more source