Results 21 to 30 of about 905,382 (336)
Growth hormone: isoforms, clinical aspects and assays interference
Clinical Diabetes and Endocrinology, 2018 The measurement of circulating concentrations of growth hormone (GH) is an indispensable tool in the diagnosis of both GH deficiency and GH excess. GH is a heterogeneous protein composed of several molecular isoforms, but the physiological role of these ...
Júnia Ribeiro de Oliveira Longo Schweizer +2 more
doaj +1 more source
Long‐acting growth hormone in 2022
Pediatric Investigation, 2023 After the isolation of pituitary growth hormone (GH) in 1957, this form of GH, always in limited supply, was the only drug available for the treatment of GH deficiency.
Margaret Steiner +2 more
doaj +1 more source
TREATMENT OF GROWTH-HORMONE DEFICIENCY WITH GROWTH-HORMONE-RELEASING HORMONE
The Lancet, 1987 18 prepubertal growth-hormone (GH)-deficient children were treated with twice-daily subcutaneous injections of a growth-hormone-releasing hormone analogue, GHRH (1-29) NH2. In 12 of the children the height velocity rose on GHRH treatment, and 8 were judged to have shown a worthwhile response to therapy in that their height velocities during the first 6
Ross, R.J.M. +8 more
openaire +3 more sources
Long acting growth hormone (LAGH), an update
Frontiers in Pediatrics, 2023 In 1957, Maurice Raben at Yale was able to isolate and purify growth hormone from cadaveric pituitary glands. Pituitary growth hormone was the only way to treat children with growth hormone (GH) deficiency, until 1985 when recombinant GH became available
Margaret Steiner Grillo +2 more
doaj +1 more source
Growth hormone in growth hormone deficiency [PDF]
BMJ, 2002 Papers p 70 With the advent of an unlimited supply of recombinant DNA growth hormonesome 15 years ago endocrinologists and paediatricians hoped that the majorgoal in treating children with growth hormone deficiency—that is, a near normal adult height—would finally be achievable.
openaire +2 more sources
Growth Hormone Releasing Hormone and Growth Hormone: Genetic Studies in Familial Growth Hormone Deficiency [PDF]
Pediatric Research, 1985 Four families with growth hormone (GH) deficiency, either isolated or with other pituitary hormonal deficits are described. Members of each underwent pharmacological testing for GH secretion and infusions of GH releasing hormone (GHRH) to determine the locus of the defect in GH secretion.
Richard W. Furlanetto +6 more
openaire +2 more sources
Oman Medical Journal, 2017 Objectives: The use of growth hormone (GH) in idiopathic short stature (ISS) has been a subject of debate for the past two decades. We sought to assess the effect of GH on final height (FH) in patients with ISS in our region, which has a high ...
Shireen Mreish +2 more
doaj +1 more source
Common polymorphisms of growth hormone: Growth hormone receptor axis in Turkish children with short stature [PDF]
, 2022 Objective: A single-nucleotide polymorphism of the growth hormone 1 gene, GH1IVS4+90A>T (rs2665802), associated with short stature and a polymorphism of the growth hormone receptor gene, exon 3 deleted variant, associated with increased responsiveness to
Adal, Servet Erdal +5 more
core +1 more source
The action of the plant growth hormone [PDF]
, 1933 Although the control of cell elongation in plant tissues by a special growth-promoting substance or substances has been well established for some time, the processes by which this substance is able to bring about growth have remained obscure.
Bonner, James
core +2 more sources
TSH-CHECK-1 test: diagnostic accuracy and potential application to initiating treatment for hypothyroidism in patients on anti-tuberculosis drugs. [PDF]
, 2012 Thyroid-stimulating hormone (TSH) promotes expression of thyroid hormones which are essential for metabolism, growth, and development. Second-line drugs to treat tuberculosis (TB) can cause hypothyroidism by suppressing thyroid hormone synthesis ...
A MacGregor +17 more
core +7 more sources