Growth Hormone Stimulation Testing: To Test or Not to Test? That Is One of the Questions
Frontiers in Endocrinology, 2022 The evaluation of children with short stature includes monitoring over a prolonged period to establish a growth pattern as well as the exclusion of chronic medical conditions that affect growth.
Mabel Yau, Robert Rapaport
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Mìžnarodnij Endokrinologìčnij Žurnal, 2013 In this article authors discussed the results of literature review, which has been dedicated to study of different complications of growth hormone deficiency in adults, referring to the literature of the last 10–15 years.
S.I. Ismailov +3 more
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Hyperinsulinemic Hypoglycemia and Growth Hormone Deficiency Secondary to 20p11 Deletion
Case Reports in Endocrinology, 2023 Hypoglycemia is concerning for neurological complications in infants and children. Determining the cause of hypoglycemia is essential in providing appropriate treatment.
Erica Wee +5 more
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Modeling of mouse experiments suggests that optimal anti-hormonal treatment for breast cancer is diet-dependent [PDF]
arXiv, 2023 Estrogen receptor positive breast cancer is frequently treated with anti-hormonal treatment such as aromatase inhibitors (AI). Interestingly, a high body mass index has been shown to have a negative impact on AI efficacy, most likely due to disturbances in steroid metabolism and adipokine production.
arxiv
Genetics of Growth Disorders-Which Patients Require Genetic Testing? [PDF]
, 2019 The second 360° European Meeting on Growth Hormone Disorders, held in Barcelona, Spain, in June 2017, included a session entitled Pragmatism vs. Curiosity in Genetic Diagnosis of Growth Disorders, which examined current concepts of genetics and growth in
Argente, J +3 more
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Deprenyl, an old drug with new anticancer potential: Mini review [PDF]
arXiv, 2021 The anticancer potential of monoamine oxidase (MAO) was observed in pre-clinical assays conducted with cell cultures and animals. L-Deprenyl (DEP) causes apoptosis in melanoma, leukemia and mammary cells. High-dose DEP has shown toxicity in mammary and pituitary cancers, as well as in monoblastic leukemia, in rats.
arxiv
Anophthalmia, hearing loss, abnormal pituitary development and response to growth hormone therapy in three children with microdeletions of 14q22q23 [PDF]
, 2014 BACKGROUND: Microdeletions of 14q22q23 have been associated with eye abnormalities and pituitary defects. Other phenotypic features in deletion carriers including hearing loss and response to growth hormone therapy are less well recognized.
Audrey Briand-Suleau +14 more
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Efficacy of growth hormone therapy in adults with childhood-onset growth hormone deficiency [PDF]
Annals of Pediatric Endocrinology & Metabolism, 2014 PurposeGrowth hormone (GH) plays a key role in the regulation of body composition, lipid metabolism, and quality of life in adults with GH deficiency (GHD).
Ja Hye Kim +3 more
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Mass Spectrometry-An Alternative in Growth Hormone Measurement [PDF]
Bioanalysis 6 (2014) 2391-2402, 2014 Growth hormone (GH) constitutes a set of closely related protein isoforms. In clinical practice, the disagreement of test results between commercially available ligand-binding assays is still an ongoing issue, and incomplete knowledge about the particular function of the different forms leaves an uncertainty of what should be the appropriate measurand.
arxiv +1 more source
Aetiology of growth hormone deficiency. [PDF]
Archives of Disease in Childhood, 1987 A retrospective analysis was performed in an attempt to identify perinatal risk factors for the development of growth hormone deficiency. More of the affected children were boys, and their birth weights were significantly lower than those of the national average; there were also considerably more preterm and post-term deliveries among boys.
S M Herber, R Kay
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