Results 71 to 80 of about 304,424 (378)

Pituitary deficiency after aneurysmal subarachnoid hemorrhage [PDF]

open access: yes, 2013
OBJECTIVE: Aneurysmal subarachnoid hemorrhage puts patients at high risk for the development of pituitary insufficiency. We evaluated the incidence of pituitary dysfunction in these patients and its correlation with clinical outcome ...
Albuquerque, Lucas Alverne Freitas de   +10 more
core   +4 more sources

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu   +7 more
wiley   +1 more source

Growth Hormone Deficiency

open access: yesGüncel Pediatri, 2010
Growth hormone deficiency is the most promising entity in terms of response to therapy among the treatable causes of growth retardation. It may be due to genetic or acquired causes.
Ömer Tarım, Halil Sağlam
doaj  

The Effects of Growth Hormone Treatment in Patients with Isolated Growth Hormone Deficiency on Hematological Parameters

open access: yesTrends in Pediatrics, 2021
Objective: A small number of studies were reported regarding the direct and indirect effects of growth hormone (GH) and insulin-like growth factor-1 (IGF-1) especially on the erythrocyte series. The purpose of this study was to examine the effects of GH
Derya Şengün, Atilla Çayır
doaj   +1 more source

Growth of Solutions of Second Order Complex Linear Differential Equations [PDF]

open access: yesarXiv, 2022
We study about order of growth and hyper order of growth of non trivial solutions of second order linear differential equations, having restrictions in the coefficients. These restrictions involve notions of Yang's inequality, Borel exceptional value, deficient value and accumulation ray.
arxiv  

Genetic and non-genetic causes of Isolated Growth Hormone Deficiency and Combined Pituitary Hormone Deficiency: Results of the HYPOPIT study [PDF]

open access: yes, 2008
Hypopituitarism, the deficiency of one or more pituitary hormones, causes stunted growth and severe health problems. Understanding the etiology of pituitary hormone deficiencies is important for anticipation of clinical problems, for genetic counselling ...
Graaff, L.C.G. (Laura) de
core   +1 more source

Growth hormone treatment in non-growth hormone-deficient children [PDF]

open access: yesAnnals of Pediatric Endocrinology & Metabolism, 2014
Until 1985 growth hormone (GH) was obtained from pituitary extracts, and was available in limited amounts only to treat severe growth hormone deficiency (GHD). With the availability of unlimited quantities of GH obtained from recombinant DNA technology, researchers started to explore new modalities to treat GHD children, as well as to treat a number of
Chiara Guzzetti   +3 more
openaire   +3 more sources

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

open access: yesMolecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi   +5 more
wiley   +1 more source

Neurofibromatosis 1 and Growth Hormone Deficiency

open access: yesPediatric Neurology Briefs, 2000
The growth profiles and growth hormone levels of children with neurofibromatosis 1 (NF-1) were analyzed at the University of Texas Medical School, Houston, TX.
J Gordon Millichap
doaj   +1 more source

Individual participant data from digital sources informed and improved precision in the evaluation of predictive biomarkers in Bayesian network meta-analysis [PDF]

open access: yesarXiv, 2023
Objective: We aimed to develop a meta-analytic model for evaluation of predictive biomarkers and targeted therapies, utilising data from digital sources when individual participant data (IPD) from randomised controlled trials (RCTs) are unavailable. Methods: A Bayesian network meta-regression model, combining aggregate data (AD) from RCTs and IPD ...
arxiv  

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