Results 131 to 140 of about 60,269 (268)

Fasting and postprandial plasma ghrelin levels are decreased in patients with liver failure previous to liver transplantation [PDF]

, 2009
[Abstract] Anorexia is a problem of paramount importance in patients with advanced liver failure. Ghrelin has important actions on feeding and weight homeostasis. Concentrations of ghrelin are controversial in liver cirrhosis.
A Asakawa, A Caixas, A Laviano, AJ Lely van der, AL Barkan, AM Haqq, AM Madden, AM Wren, B Otto, C Gauna, C Gauna, C Matos, DE Cummings, DE Cummings, DE Cummings, DE Flanagan, DR Matthews, E Kalaitzakis, ET Vestergaard, F Cordido, F Tacke, Fernando Cordido, FM Toorn Van der, Francisco Suarez, G Marchesini, G Marchesini, G Muccioli, G Murdolo, G Schaller, H Ataseven, H Hosoda, H Takahashi, HIM Davidson, HJ Kim, HU Lautz, I Bedendi, J Kozakowski, J Liu, J Ockenga, Jesús Garcia-Buela, K Toshinai, KE Foster-Schubert, M Breidert, M Granado, M Hotta, M Kojima, M Kojima, M Merli, M Nakazato, M Perez-Fontán, M Perez-Fontán, M Pérez-Fontán, M Tschop, M Tschop, M Tschöp, MA Bednarek, Maria Teresa Diz-Lois, ML Isidro, NM Thompson, O Kasımay, O Selberg, O Ukkola, Ovidio Vidal, P Alvarez, P Cassoni, PU Freda, R Nass, SO Işeri, Susana Sangiao-Alvarellos, T McLaughlin, T Shiiya, V Cappiello, WAM Blom, X Zhu, Y Shuto, Z Jarkovska   +75 more
core   +2 more sources

Ghrelin: An Emerging Therapy for Heart Failure

Clinical Endocrinology, Volume 102, Issue 4, Page 403-412, April 2025.
ABSTRACT Objective Ghrelin is emerging as a promising therapeutic option for heart failure (HF) due to its potent inotropic, anabolic, and cardioprotective properties. This review aims to critically examine the available clinical evidence on ghrelin therapy in HF, while also incorporating key findings from preclinical studies that support its ...
Nikolaos Theodorakis, Georgios Feretzakis, Magdalini Kreouzi, Dimitrios Anagnostou, Christos Hitas, Vassilios S. Verykios, Maria Nikolaou   +6 more
wiley   +1 more source

Ghrelin receptor in two species of anuran amphibian, bullfrog (Rana catesbeiana) and Japanese tree frog (Hyla japonica)

Frontiers in Endocrinology, 2011
We identified cDNA encoding a functional growth hormone secretagogue-receptor 1a (GHS-R1a, ghrelin receptor) in two species of anuran amphibian, bullfrog (Rana catesbeiana) and Japanese tree frog (Hyla japonica). Deduced receptor protein for bullfrog and
Hiroyuki eKaiya, Yasushi eKoizumi, Norifumi eKonno, Kazutoshi eYamamoto, Minoru eUchiyama, Kenji eKangawa, Mikiya eMiyazato   +6 more
doaj   +1 more source

Molecular characterization of the bovine GHRL gene [PDF]

, 2009
peer reviewedaudience: researcherBovine ghrelin, a 27 amino acid pepticle, has been identified in oxyntic glands of the abomasum. It is an endogenous ligand for growth hormone secretagogue receptor and stimulates food intake and growth hormone secretion.
Colinet, Frédéric, Portetelle, Daniel, Renaville, Robert   +2 more
core   +1 more source

Ghrelin and des-octanoyl ghrelin promote adipogenesis directly in vivo by a mechanism independent of the type 1a growth hormone secretagogue receptor.

Endocrinology, 2004
Ghrelin promotes fat accumulation, despite potent stimulation of the lipolytic hormone, GH. The function of the major circulating isoform of ghrelin, des-octanoyl ghrelin, is unclear, because it does not activate the GH secretagogue receptor (GHS-R1a ...
N. Thompson, Dave A S Gill, R. Davies, N. Loveridge, P. Houston, I. Robinson, T. Wells   +6 more
semanticscholar   +1 more source

Genetic linkage and association of the growth hormone secretagogue receptor (ghrelin receptor) gene in human obesity.

Diabetes, 2005
The growth hormone secretagogue receptor (GHSR) (ghrelin receptor) plays an important role in the regulation of food intake and energy homeostasis. The GHSR gene lies on human chromosome 3q26 within a quantitative trait locus strongly linked to multiple ...
A. Baessler, M. Hasinoff, M. Fischer, Wibke Reinhard, G. Sonnenberg, M. Olivier, J. Erdmann, H. Schunkert, A. Doering, H. Jacob, A. Comuzzie, A. Kissebah, A. Kwitek   +12 more
semanticscholar   +1 more source

Nucleus accumbens ghrelin signaling controls anxiety-like behavioral response to acute stress

Behavioral and Brain Functions
Background Anxiety disorders are one of the most common mental disorders. Ghrelin is a critical orexigenic brain-gut peptide that regulates food intake and metabolism.
Leilei Chang, Yecheng He, Tian Tian, Bin Li   +3 more
doaj   +1 more source

Therapeutic applications of ghrelin agonists in the treatment of gastroparesis [PDF]

, 2015
There remains an unmet need for effective pharmacologic treatments for gastroparesis. Ghrelin is the endogenous ligand for the growth hormone secretagogue receptor and has been shown to regulate energy homeostasis and exert prokinetic effects on ...
Shin, Andrea, Wo, John M.
core   +1 more source

Identification of a long non-coding RNA gene, growth hormone secretagogue receptor opposite strand, which stimulates cell migration in non-small cell lung cancer cell lines.

International Journal of Oncology, 2013
The molecular mechanisms involved in non‑small cell lung cancer tumourigenesis are largely unknown; however, recent studies have suggested that long non-coding RNAs (lncRNAs) are likely to play a role.
E. Whiteside, I. Seim, Jana P Pauli, Angela J O'Keeffe, Patrick B. Thomas, Shea L. Carter, C. Walpole, J. Fung, P. Josh, A. Herington, L. Chopin   +10 more
semanticscholar   +1 more source

The effect of intravenous injection of Ghrelin on the mean plasma concentrations of insulin in immature camels fed different levels of their energy requirements [PDF]

Āsīb/shināsī-i Darmāngāhī-i Dāmpizishkī, 2009
Ghrelin is a peptide hormone secreted into the circulation from the stomach, but this peptide is also synthetized in a number of different body tissues including the brain and pancreas, suggesting both endocrine and paracrine effects.
doaj