Results 231 to 240 of about 7,661,292 (297)

Growth hormone therapy in a patient with short stature due to fetal alcohol syndrome: seven-year follow-up. [PDF]

Clin Pediatr Endocrinol
Yoshida K, Okamatsu Y, Kanda H, Yatsuga S.   +3 more
europepmc   +1 more source

Loss of LCN2 Function Ameliorates Glucocorticoid‐Induced Muscle Atrophy via Remodeling the Extracellular Matrix

Advanced Science, EarlyView.
Glucocorticoids transcriptionally activate LCN2 expression via GR nuclear translocation. Secreted LCN2 binds MMP9 to degrade skeletal muscle ECM collagen, blocks integrin‐mediated mechanotransduction, bidirectionally disrupts muscle protein homeostasis, and reveals a novel target for steroid‐induced muscle atrophy.
Hongwei Shi, Xiaojing Hao, Yi Yan, Fengyang Li, Yaru Zhang, Zixin Li, Wenjuan Xie, Jiayin Lu, Xiaomao Luo, Yanjun Dong, Haidong Wang, Juan Wang   +11 more
wiley   +1 more source

Adherence to recombinant human growth hormone therapy in children: influencing factors and clinical implications. [PDF]

Front Pediatr
Chang W, Jin H, Zhou Q, Ye K, Dai Y.
europepmc   +1 more source

Encapsulated Leptin‐Producing Cells Facilitate Entrainment of Circadian Rhythms in Rodents and Nonhuman Primates

Advanced Science, EarlyView.
A clinically translatable cell line can be engineered to produce leptin, encapsulated in biomaterial and safely implanted to produce and deliver the metabolic regulating protein within the body. Implantation of these encapsulated cells decreases the time it takes for mice and non‐human primates to adjust to circadian disruptions similar to those ...
Samantha T. Fleury, Xuanyi Lin, Peter D. Rios, Christopher Olker, Eun Joo Song, Alejandra Cobos Perez, Cody Fell, Daisy Lopez, Ira Joshi, Hafsa Nasir, Cecelia Curtis, Danna Muringi, Kaiyuan Wang, José Oberholzer, Fred W. Turek, Isaac B. Hilton, Jonathan Rivnay, Martha Hotz Vitaterna, Omid Veiseh   +18 more
wiley   +1 more source

Impact of COVID-19 on growth hormone therapy efficacy in pediatric patients with short stature. [PDF]

Endocr Connect
Kim YM, Oh AR, Han HS, Yu J, Yu J, Lee TK, Lee GM, Choe J, Oh JS, Lim HH.   +9 more
europepmc   +1 more source

SPARC Drives Podocyte Mitochondrial Damage and Ferroptosis in Diabetic Kidney Disease Following Klotho Deficiency

Advanced Science, EarlyView.
Klotho deficiency promotes podocyte mitochondrial dysfunction and ferroptosis through activation of the PKCα/CUX1/SPARC/TGFβ‐RII axis. SPARC emerges as a key mediator linking Klotho loss to podocyte injury in DKD and other kidney injury models, suggesting broader implications for CKD progression.
Qing Yang, Huimin Jiang, Chenyang Xiong, Xindi Zhou, Qinqin Tan, Han Xiao, Lan Qiu, Chun Gan, Yaxi Chen, Haiping Yang, Wei Jiang, Qiu Li   +11 more
wiley   +1 more source

Growth Hormone Therapy in Children Born Small for Gestational Age with Persistent Short Stature: Lessons Learned from Real-World International Databases and Directions for Future Research.

Horm Res Paediatr
Samvelyan S, Ahmed SF, Alimussina M, Kodytkova A, Jirova B, Amaratunga SA, Lebl J.   +6 more
europepmc   +1 more source

The role of digital health in growth hormone therapy: perspectives from Gulf Cooperation Council pediatric endocrinologists. [PDF]

Front Endocrinol (Lausanne)
Kaplan W, Alherbish A, Aljnaibi A, Alsagheir A, Almutair A, Farooque A, Deeb A, Abbas BB, Jubeh JA, Attia N, Thalange N, Salem Al Remeithi S, Dimitri P, Rivera-Romero O, Koledova E.   +14 more
europepmc   +1 more source

Suprasellar CNS germ cell tumors and endocrine sequelae: early growth hormone therapy as a contributor to height gain: a single institute analysis. [PDF]

Childs Nerv Syst
Suda A, Fukushima H, Takarada A, Suzuki R, Iwabuchi A, Muroi A, Mizumoto M, Takada H.   +7 more
europepmc   +1 more source

Myokine Levels in Relation to Bone Markers and Adipokines in Children with Prader-Willi Syndrome During Growth Hormone Therapy and Dietary Intervention. [PDF]

Int J Mol Sci
Gajewska J, Chełchowska M, Szamotulska K, Strucińska M, Klemarczyk W, Ambroszkiewicz J.   +5 more
europepmc   +1 more source