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Noonan syndrome spectrum disorders in real life: patient characteristics and response to growth hormone therapy in a genetically defined single-country multicenter cohort. [PDF]

open access: yesEur J Pediatr
Jirova B   +20 more
europepmc   +1 more source

Comparison of growth hormone releasing hormone therapy and growth hormone therapy in growth hormone deficiency

European Journal of Pediatrics, 1989
Seven children with growth hormone deficiency of hypothalamic origin responded to an i.v. bolus of growth hormone releasing hormone (GHRH) (1-29)-NH2 with a mean serum increase of 10.7 ng/ml growth hormone (GH) (range 2.5-29.3 ng/ml). Continuous s.c.
O Butenandt
exaly   +3 more sources

Growth Hormone Therapy in Adults

Frontiers in Neuroendocrinology, 2001
The importance of growth hormone (GH) deficiency in adults became evident 10 to 15 years ago, when the first clinical studies on GH replacement therapy in adults were published. Since then, a number of studies have been reported showing that GH replacement therapy can improve this condition.
Jens Otto Lunde Jörgensen   +2 more
exaly   +3 more sources

Growth Hormone Therapy in Adults

Annual Review of Medicine, 2003
Growth hormone (GH) is classically linked with linear growth in childhood but continues to have important metabolic actions throughout life. GH deficiency in adulthood causes a distinct syndrome with significant morbidities. These include increased total and visceral fat, decreased muscle mass and aerobic capacity, affective disturbances, abnormal ...
George R Merriam, David E Cummings
exaly   +3 more sources

Growth hormone therapy

The Indian Journal of Pediatrics, 2005
Growth hormone (GH) therapy has revolutionized treatment of children with growth hormone deficiency (GHD). Improved height outcome with final height in the target height range has been achieved in these children. Identification of Creutzfeldt-Jakob disease, a deadly prion mediated disorder, in recipients of pituitary GH accelerated the transition from ...
Anurag, Bajpai, P Sn, Menon
openaire   +2 more sources

Growth hormone therapy for adult growth hormone deficiency

Trends in Endocrinology & Metabolism, 1996
GH deficiency in adult life is associated with a number of adverse biological changes including osteopenia, reduced exercise capacity, altered body composition, deleterious alterations in the lipid profile and insulin status, and reduced quality of life. Potentially, most of these changes can be reversed by GH replacement therapy.
S M, Shalet, A, Rahim, A A, Toogood
openaire   +2 more sources

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