Results 121 to 130 of about 11,873,006 (292)

Analysis of Craniofacial and Extremity Growth in Patients with Growth Hormone Deficiency during Growth Hormone Therapy

, 2009
Background/Aims: There are many controversies regarding side effects on craniofacial and extremity growth due to growth hormone ( GH) treatment. Our aim was to estimate GH action on craniofacial development and extremity growth in GH-deficient patients ...
ARNHOLD, Ivo Jorge Prado, ROSSETTO, Shirley M., BERGER, Karina, AMARAL, Terezinha Sampaio, MENDONCA, Berenice Bilharinho, FARIA, Maria Estela Justamante de, CARVALHO, Luciani R.   +6 more
core   +1 more source

Recombinant growth hormone for children with systemic lupus erythematosus and linear growth delay: A report of two cases and literature review

Journal of International Medical Research
Linear growth delay is common in children with systemic lupus erythematosus. There have been scattered reports of using recombinant human growth hormone in these children, but safety remains a major concern.
Fujuan Liu, Xiaoying Yuan, Yanjun Yang, Yanan Han, Lanlan Ge, Jingxiao Guo, Ling Liu, Chunzhen Li, Dongfeng Zhang   +8 more
doaj   +1 more source

Treatment with long-acting growth hormone: effectiveness and safety

Frontiers in Endocrinology
Long-acting growth hormone (GH) formulations represent a clinically effective alternative to daily recombinant human GH (rhGH) administration, enabling extended dosing intervals and enhancing patient adherence. This approach is particularly beneficial in
Livia Basile, Rossella Cannarella, Rosita A. Condorelli, Francesco Frasca, Aldo E. Calogero, Sandro La Vignera   +5 more
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Weekly Growth Hormone Somatrogon and Clinical Use Principles

Güncel Pediatri
The recombinant human growth hormone has been used for about 40 years and is administered as a single daily dose. Long-acting growth hormones are developed to enhance therapy adherence and reduce therapy load.
Erdal Eren, Furkan Erdoğan
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

Regulation of the juvenile hormone titre in the Colorado potato beetle [PDF]

, 1978
Three main topics were investigated in regulation of the titre of juvenile hormone in haemolymph of the Colorado potato beetle ( Leptinotarsa decemlineata Say): enzymic breakdown of the hormone; binding and protection of the hormone by carrier proteins ...
Kramer, S.J.
core  

Growth hormone attenuates skeletal muscle changes in experimental chronic heart failure

, 2010
Objective: This study evaluated the effects of growth hormone (GH) on morphology and myogenic regulatory factors (MRF) gene expression in skeletal muscle of rats with ascending aortic stenosis (AAS) induced chronic heart failure.Design: Male 90-100 g ...
dos Santos, Denis Pioli, Padovani, Carlos Roberto, Okoshi, Katashi [UNESP], Alves de Almeida, Fernanda Losi, Seiva, Fabio R. F. [UNESP], Moreira, Vanessa O., Padovani, Carlos Roberto [UNESP], dos Santos, Denis Pioli [UNESP], Cicogna, Antonio Carlos [UNESP], Okoshi, Marina Politi, Alves de Almeida, Fernanda Losi [UNESP], Barros Castro, Ana Valeria, Moreira, Vanessa O. [UNESP], Dal Pai-Silva, Maeli [UNESP], Barros Castro, Ana Valeria [UNESP], Carvalho, Robson Francisco [UNESP], Okoshi, Katashi, Okoshi, Marina Politi [UNESP], Carvalho, Robson Francisco, Cicogna, Antonio Carlos, Dal Pai-Silva, Maeli, Seiva, Fabio R. F.   +21 more
core   +1 more source