Results 131 to 140 of about 870,777 (309)
, 2014 Injuries to the growth plate cartilage often lead to bony repair, resulting in bone growth defects such as limb length discrepancy and angulation deformity in children.
Xian, C., Chung, R.
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Histochemical analysis of growth plate cartilage.
, 2014 A) Haematoxylin and eosin staining of wild type and CHOP null growth plates at 3 weeks of age showing normal columnar organisation of chondrocytes in the growth plates of both genotypes and delineating the resting (RZ), proliferating (PZ) and ...
Poonam Halai (524008) +6 more
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Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Buckling and Post-Buckling Analysis of Cracked Plates by The Boundary Element Method
, 2003 PhDThis thesis presents boundary element formulations for buckling and nonlinear buckling analysis of plates. Dual boundary element formulations are also presented for linear and nonlinear buckling, and large deformation analysis of crack behaviour in
Purbolaksono, Judha
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Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Growth plate injuries of long tubular bones [PDF]
, 2016 Hrskavične ploče rasta su strukture unutar kostiju koje se nalaze između metafize i epifize u djece i adolescenata. Sastoje se od proliferirajućeg hrskavičnog tkiva koje enhondralno okoštava te je zaslužno za uzdužni rast kosti. Svaka duga kost ima barem
Bagić, Marko
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