Results 1 to 10 of about 18,120 (213)

Effect of arsenic in endochondral ossification of experimental animals

Experimental and Toxicologic Pathology, 2010
Arsenic (As) toxicity is a global health problem affecting millions of people, the most toxic forms being Arsenites [As(III)] and Arsenates [As(V)]. Arsenic intoxication can occur through different exposure routes. The aim of the present work was to determine the effect of As on endochondral ossification and bone remodeling in experimental animals, by ...
Aybar Odstrcil, Ana del Carmen, Acebal, Silvia Graciela, Diaz Ricci, Juan Carlos, Mandalunis, Patricia Mónica   +3 more
openaire   +3 more sources

Mechanism of Piezo1 regulating chondrocyte mitochondrial function and promoting fracture healing through β-catenin/LARS2 signaling pathway

Bone Research
Piezo1, a key mechanosensor in bone homeostasis, plays a crucial role in fracture healing. However, the mechanisms through which Piezo1 regulates chondrocytes and affects endochondral ossification remain poorly understood. This study aimed to investigate
Tao Zhang, Hongzhi Lv, Siming Jia, Lijun Wang, Weijian Liu, Kai Ding, Xiaofeng Du, Guangzhao Hou, Zhiyong Hou, Yingze Zhang, Weiguo Zou, Wei Chen, Yanbin Zhu   +12 more
doaj   +1 more source

Biomaterial-based endochondral bone regeneration: a shift from traditional tissue engineering paradigms to developmentally inspired strategies

Materials Today Bio, 2019
There is an urgent, clinical need for an alternative to the use of autologous grafts for the ever increasing number of bone grafting procedures performed annually.
E.J. Sheehy, D.J. Kelly, F.J. O'Brien
doaj   +1 more source

Local injections of β-NGF accelerates endochondral fracture repair by promoting cartilage to bone conversion

Scientific Reports, 2020
There are currently no pharmacological approaches in fracture healing designed to therapeutically stimulate endochondral ossification. In this study, we test nerve growth factor (NGF) as an understudied therapeutic for fracture repair.
Kevin O. Rivera, Fabrizio Russo, Ryan M. Boileau, Ryan E. Tomlinson, Theodore Miclau, Ralph S. Marcucio, Tejal A. Desai, Chelsea S. Bahney   +7 more
doaj   +1 more source

Effect of alendronate on endochondral ossification in mandibular condyles of growing rats

European Journal of Histochemistry, 2012
The replacement of the calcified cartilage by bone tissue during the endochondral ossification of the mandibular condyle is dependent of the resorbing activity of osteoclats.
V. Bradaschia-Correa, F.A.C. Barrence, L.B. Ferreira, L.F. Massa, V.E. Arana-Chavez   +4 more
doaj   +1 more source

Histological and Histomorphometric illustration the endochondral ossification of the mandibular angle defect repair in rats after oral stimulation with bisphosphonate treatment (an in vivo study)

Diyala Journal of Medicine
Background: Bio-phosphonates can be used to lower the risk of hip and spine fractures. Additionally, they can be used to treat Paget's disease of the bones in a variety of dosages.
Manar Abd Alrazaq Hassan,, Ansam Mahdi Khalel,, Asmaa A. Ajwad ,, Ali hakiem tawfieq   +3 more
doaj   +1 more source

endochondral ossification

Citation: 'endochondral ossification' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.10656 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests for
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Histology of epiphyseal cartilage calcification and endochondral ossification

Frontiers in Bioscience, 2012
Cartilage calcification is carried out by chondrocytes as they hypertrophy and begin to secrete matrix vesicles. Calcification initiates when calcium phosphates appear inside these matrix vesicles, forming hydroxyapatite crystals that eventually break through the membrane to form calcifying globules, as in bone calcification. However, the extracellular
Norio, Amizuka, Tomoka, Hasegawa, Kimimitsu, Oda, Paulo Henrique, Luiz de Freitas, Kazuto, Hoshi, Minqi, Li, Hidehiro, Ozawa   +6 more
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Trpv4-Mediated Mitophagy Regulates Endochondral Ossification In The Condylar Cartilage

International Dental Journal
Aim or purpose: This study aims to elucidate the mechanism by which mouth breathing-induced condylar stress change (MB-CSC) disrupts endochondral ossification in the posterior zone of condyle.
Fei Liu, Ying Zhao
doaj   +1 more source

Biphasic biomimetic scaffolds based on a regionally decalcified bone framework and pre-chondrogenic microspheres for osteochondral defect repair

Materials Today Bio
Osteochondral defects are still facing a significant challenge in clinical surgery, making post-trauma repair difficult. Tissue engineering has provided a promising approach to solving these defects.
Zhuo Liang, Qingqing Pan, Fei Xue, Jingdi Zhang, Zhenlin Fan, Weiyun Wang, Xueqiang Guo, Zhuang Qian, Yaping Shen, Wenjuan Song, Lei Wang, Guangdong Zhou, Yong He, Wenjie Ren   +13 more
doaj   +1 more source