Results 21 to 30 of about 36,224 (218)
Epidermal growth factor signalling pathway in endochondral ossification: an evidence-based narrative review [PDF]
Annals of Medicine, 2022 Giuseppe M. Peretti
exaly +2 more sources
Regenerative Therapy, 2023 Vertebrates form their skeletal tissues from three distinct origins (the neural crest, paraxial mesoderm, and lateral plate mesoderm) through two distinct modes of ossification (intramembranous and endochondral ossification).
Yuki Ikeda +14 more
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The role of computational models in mechanobiology of growing bone
Frontiers in Bioengineering and Biotechnology, 2022 Endochondral ossification, the process by which long bones grow in length, is regulated by mechanical forces. Computational models, specifically finite element models, have been used for decades to understand the role of mechanical loading on ...
Ester Comellas, Sandra J. Shefelbine
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Sox9 potentiates BMP2-induced chondrogenic differentiation and inhibits BMP2-induced osteogenic differentiation. [PDF]
PLoS ONE, 2014 Bone morphogenetic protein 2 (BMP2) is one of the key chondrogenic growth factors involved in the cartilage regeneration. However, it also exhibits osteogenic abilities and triggers endochondral ossification.
Junyi Liao +16 more
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Failures of Endochondral Ossification in the Mucopolysaccharidoses
Current Osteoporosis Reports, 2020 The mucopolysaccharidoses (MPS) are a group of inherited lysosomal storage disorders characterized by abnormal accumulation of glycosaminoglycans (GAGs) in cells and tissues. MPS patients frequently exhibit failures of endochondral ossification during postnatal growth leading to skeletal deformity and short stature.
Zhirui Jiang +3 more
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Characterization of early mouse mesenchymal stem/progenitor cells for generating cartilage and study their role in endochondral ossification [PDF]
, 2016 Mesenchymal stem/ stromal cells (MSCs) isolated from mice have allowed to address some of the major issues that could not be investigated by using human MSCs.
Jaiswal, Sumit
core +1 more source
Zfhx4 regulates endochondral ossification as the transcriptional platform of Osterix in mice
Communications Biology, 2021 Nakamura et al. used expression studies to identify an enrichment of Zfhx4 in cartilage and revealed through global gene knock-down that it is required for proper endochondral ossification in mice.
Eriko Nakamura +16 more
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Matrix remodeling during endochondral ossification [PDF]
Trends in Cell Biology, 2004 Endochondral ossification, the process by which most of the skeleton is formed, is a powerful system for studying various aspects of the biological response to degraded extracellular matrix (ECM). In addition, the dependence of endochondral ossification upon neovascularization and continuous ECM remodeling provides a good model for studying the role of
Nathalie, Ortega +2 more
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Transcriptional Network Controlling Endochondral Ossification [PDF]
Journal of Bone Metabolism, 2017 Endochondral ossification is the fundamental process of skeletal development in vertebrates. Chondrocytes undergo sequential steps of differentiation, including mesenchymal condensation, proliferation, hypertrophy, and mineralization. These steps, which are required for the morphological and functional changes in differentiating chondrocytes, are ...
Hata, Kenji +3 more
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Revista Colombiana de Endocrinología, Diabetes y Metabolismo, 2018 El presente artículo tiene como objetivo presentar de forma resumida los diferentes factores que están involucrados en la diferenciación y el mantenimiento del fenotipo óseo, en contraste con los factores adipogénicos, cuya expresión determina procesos ...
Pedro Sánchez Márquez +1 more
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