Results 21 to 30 of about 18,079 (225)

Absence of endochondral ossification and craniosynostosis in posterior frontal cranial sutures of Axin2(-/-) mice. [PDF]

PLoS ONE, 2013
During the first month of life, the murine posterior-frontal suture (PF) of the cranial vault closes through endochondral ossification, while other sutures remain patent. These processes are tightly regulated by canonical Wnt signaling.
Björn Behr, Michael T Longaker, Natalina Quarto   +2 more
doaj   +2 more sources

Inhibition of cyclooxygenase-2 impacts chondrocyte hypertrophic differentiation during endochondral ossification [PDF]

European Cells & Materials, 2011
Skeletogenesis and bone fracture healing involve endochondral ossification, a process during which cartilaginous primordia are gradually replaced by bone tissue.
TJM Welting, MMJ Caron, PJ Emans, MPF Janssen, K Sanen, MME Coolsen, L Voss, DAM Surtel, A Cremers, JW Voncken, LW van Rhijn   +10 more
doaj   +2 more sources

Craniosynostosis of coronal suture in Twist1+/- mice occurs through endochondral ossification recapitulating the physiological closure of posterior frontal suture

Frontiers in Physiology, 2011
Craniosynostosis, the premature closure of cranial suture, is a pathologic condition that affects 1/2000 live births. Saethre-Chotzen syndrome is a genetic condition characterized by craniosynostosis.
Bjorn eBehr, Michael T Longaker, Natalina eQuarto, Natalina eQuarto   +3 more
doaj   +2 more sources

3D-printed triboelectric scaffolds for fabricating BMSC-derived cartilage to repair bone defects and promote endochondral ossification [PDF]

Bioactive Materials
The harsh microenvironment characterized by avascularity and hypoxia presents a significant challenge for bone regeneration following refractory bone defects.
Yuanqi Ma, Xingqi Song, Bin Luo, Baoshuai Bai, Chen Jin, Shanhong Xie, Meilin Huang, Jie Luo, Zhengwei You, Dong Lei, Guangdong Zhou   +10 more
doaj   +2 more sources

Endochondral ossification in the damaged joint [PDF]

, 2022
The worldwide burden of knee cartilage damage and OA is rising rapidly, especially in relatively young patients. When damaged, articular cartilage possesses little regenerative capacity. Joint homeostasis and a process called ‘endochondral ossification’ are disturbed which leads to continued joint degeneration. When total knee arthroplasty is performed
Janssen, Maarten Petrus François
openaire   +2 more sources

Epidermal growth factor signalling pathway in endochondral ossification: an evidence-based narrative review [PDF]

Annals of Medicine, 2022
L Mangiavini
exaly   +2 more sources

Modeling of intramembranous ossification using human pluripotent stem cell-derived paraxial mesoderm derivatives

Regenerative Therapy, 2023
Vertebrates form their skeletal tissues from three distinct origins (the neural crest, paraxial mesoderm, and lateral plate mesoderm) through two distinct modes of ossification (intramembranous and endochondral ossification).
Yuki Ikeda, Shoichiro Tani, Takeshi Moriishi, Aiko Kuroda, Yuki Matsuo, Naoya Saeki, Chizuko Inui-Yamamoto, Makoto Abe, Takashi Maeda, David W. Rowe, Ung-il Chung, Hironori Hojo, Yuki Matsushita, Takashi Sawase, Shinsuke Ohba   +14 more
doaj   +1 more source

The role of computational models in mechanobiology of growing bone

Frontiers in Bioengineering and Biotechnology, 2022
Endochondral ossification, the process by which long bones grow in length, is regulated by mechanical forces. Computational models, specifically finite element models, have been used for decades to understand the role of mechanical loading on ...
Ester Comellas, Sandra J. Shefelbine
doaj   +1 more source

Sox9 potentiates BMP2-induced chondrogenic differentiation and inhibits BMP2-induced osteogenic differentiation. [PDF]

PLoS ONE, 2014
Bone morphogenetic protein 2 (BMP2) is one of the key chondrogenic growth factors involved in the cartilage regeneration. However, it also exhibits osteogenic abilities and triggers endochondral ossification.
Junyi Liao, Ning Hu, Nian Zhou, Liangbo Lin, Chen Zhao, Shixiong Yi, Tingxu Fan, Wei Bao, Xi Liang, Hong Chen, Wei Xu, Cheng Chen, Qiang Cheng, Yongming Zeng, Weike Si, Zhong Yang, Wei Huang   +16 more
doaj   +1 more source

Characterization of early mouse mesenchymal stem/progenitor cells for generating cartilage and study their role in endochondral ossification [PDF]

, 2016
Mesenchymal stem/ stromal cells (MSCs) isolated from mice have allowed to address some of the major issues that could not be investigated by using human MSCs.
Jaiswal, Sumit
core   +1 more source