Endochondral Ossification of Chick Embryonic Femora in vitro and on Chorioallantoic Membrane
The Journal of Poultry Science, 2008 We observed angiogenesis and endochondral ossification of the femora of chick embryos in vitro, on chorioallantoic membrane (CAM), and in vivo to clarify the cellular processes of avian endochondral ossification. We found that the inside of the in vitro
Manami Kachi +2 more
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Advanced Science, 2021 Biomaterials play an important role in treating bone defects by promoting direct osteogenic healing through intramembranous ossification (IO). However, majority of the body's bones form via cartilaginous intermediates by endochondral ossification (EO), a
Yutong Liu +7 more
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Role of iRhoms 1 and 2 in Endochondral Ossification [PDF]
International Journal of Molecular Sciences, 2020 Growth of the axial and appendicular skeleton depends on endochondral ossification, which is controlled by tightly regulated cell–cell interactions in the developing growth plates. Previous studies have uncovered an important role of a disintegrin and metalloprotease 17 (ADAM17) in the normal development of the mineralized zone of hypertrophic ...
Renpeng Fang +8 more
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The Transcription Factor Hand1 Is Involved In Runx2-Ihh-Regulated Endochondral Ossification.
PLoS ONE, 2016 The developing long bone is a model of endochondral ossification that displays the morphological layers of chondrocytes toward the ossification center of the diaphysis.
Lindsay E Laurie +4 more
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Impairment of the chondrogenic phase of endochondral ossification in vivo by inhibition of cyclooxygenase-2 [PDF]
European Cells & Materials, 2017 Many studies have reported on the effects of cyclooxygenase-2 (COX-2) inhibition on osteogenesis. However, far less is known about the effects of COX-2 inhibition on chondrogenic differentiation.
MPF Janssen +6 more
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Potential Role of Leptin in Endochondral Ossification [PDF]
Journal of Histochemistry & Cytochemistry, 2002 Leptin, a 16-kD circulating hormone secreted mainly by white adipose tissue, is a product of the obese (ob) gene. Leptin acts on human marrow stromal cells to enhance differentiation into osteoblasts and inhibit differentiation into adipocytes. Leptin also inhibits bone formation through a hypothalamic relay.
Keiko, Kume +6 more
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Inhibition of cyclooxygenase-2 impacts chondrocyte hypertrophic differentiation during endochondral ossification [PDF]
European Cells & Materials, 2011 Skeletogenesis and bone fracture healing involve endochondral ossification, a process during which cartilaginous primordia are gradually replaced by bone tissue.
TJM Welting +10 more
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Absence of endochondral ossification and craniosynostosis in posterior frontal cranial sutures of Axin2(-/-) mice. [PDF]
PLoS ONE, 2013 During the first month of life, the murine posterior-frontal suture (PF) of the cranial vault closes through endochondral ossification, while other sutures remain patent. These processes are tightly regulated by canonical Wnt signaling.
Björn Behr +2 more
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3D-printed triboelectric scaffolds for fabricating BMSC-derived cartilage to repair bone defects and promote endochondral ossification [PDF]
Bioactive MaterialsThe harsh microenvironment characterized by avascularity and hypoxia presents a significant challenge for bone regeneration following refractory bone defects.
Yuanqi Ma +10 more
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Endochondral ossification in the damaged joint [PDF]
, 2022 The worldwide burden of knee cartilage damage and OA is rising rapidly, especially in relatively young patients. When damaged, articular cartilage possesses little regenerative capacity. Joint homeostasis and a process called ‘endochondral ossification’ are disturbed which leads to continued joint degeneration. When total knee arthroplasty is performed
Janssen, Maarten Petrus François
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