Hedgehog Signaling in Endochondral Ossification [PDF]
Journal of Developmental Biology, 2016 Hedgehog (Hh) signaling plays crucial roles in the patterning and morphogenesis of various organs within the bodies of vertebrates and insects. Endochondral ossification is one of the notable developmental events in which Hh signaling acts as a master ...
Shinsuke Ohba, Ohba Shinsuke
exaly +7 more sources
The investigation of bone fracture healing under intramembranous and endochondral ossification [PDF]
Bone Reports, 2021 After trauma, fractured bone starts healing directly through bone union or indirectly through callus formation process. Intramembranous and endochondral ossification are two commonly known mechanisms of indirect healing.
Saeed Miramini +2 more
exaly +5 more sources
Spatiotemporal Immunomodulation Using Biomimetic Scaffold Promotes Endochondral Ossification‐Mediated Bone Healing [PDF]
Advanced Science, 2021 Biomaterials play an important role in treating bone defects by promoting direct osteogenic healing through intramembranous ossification (IO). However, majority of the body's bones form via cartilaginous intermediates by endochondral ossification (EO), a
, Yuan Yuan, Wen Jiang
exaly +3 more sources
Brd4 is required for chondrocyte differentiation and endochondral ossification. [PDF]
Bone, 2022 Differentiation of multi-potent mesenchymal stromal cells (MSCs) is directed by the activities of lineage-specific transcription factors and co-factors. A subset of these proteins controls the accessibility of chromatin by recruiting histone acetyl transferases or deacetylases that regulate acetylation of the N-termini of H3 and H4 histone proteins ...
Paradise CR +10 more
europepmc +5 more sources
Close-to-native bone repair via tissue-engineered endochondral ossification approaches [PDF]
iScience, 2022 Summary: In order to solve the clinical challenges related to bone grafting, several tissue engineering (TE) strategies have been proposed to repair critical-sized defects.
Sara Nadine +3 more
doaj +5 more sources
Endochondral Ossification of Chick Embryonic Femora in vitro and on Chorioallantoic Membrane [PDF]
The Journal of Poultry Science, 2008 We observed angiogenesis and endochondral ossification of the femora of chick embryos in vitro, on chorioallantoic membrane (CAM), and in vivo to clarify the cellular processes of avian endochondral ossification. We found that the inside of the in vitro
Manami Kachi +2 more
doaj +2 more sources
Regeneration of Humeral Head Using a 3D Bioprinted Anisotropic Scaffold with Dual Modulation of Endochondral Ossification [PDF]
Advanced Science, 2023 Tissue engineering is theoretically thought to be a promising method for the reconstruction of biological joints, and thus, offers a potential treatment alternative for advanced osteoarthritis.
Tao Li +17 more
doaj +2 more sources
Endochondral ossification of the mouse nasal septum [PDF]
The Anatomical Record Part A: Discoveries in Molecular, Cellular, and Evolutionary Biology, 2006 AbstractEndochondral ossification at the caudal junctions of the cartilaginous nasal septum, in combination with interstitial expansion of the septum, is thought to displace the facial skeleton away from the neurocranium. However, the rate of endochondral ossification has not been measured or related to rates of septal enlargement.
Rosamund J, Wealthall, Susan W, Herring
exaly +3 more sources
Zfhx4 regulates endochondral ossification as the transcriptional platform of Osterix in mice [PDF]
Communications Biology, 2021 Nakamura et al. used expression studies to identify an enrichment of Zfhx4 in cartilage and revealed through global gene knock-down that it is required for proper endochondral ossification in mice.
Eriko Nakamura +16 more
doaj +2 more sources
The Transcription Factor Hand1 Is Involved In Runx2-Ihh-Regulated Endochondral Ossification. [PDF]
PLoS ONE, 2016 The developing long bone is a model of endochondral ossification that displays the morphological layers of chondrocytes toward the ossification center of the diaphysis.
Lindsay E Laurie +4 more
doaj +2 more sources