Results 261 to 270 of about 1,817,169 (352)

Can diffusion tensor imaging unlock the secrets of the growth plate? [PDF]

BJR Open
Kvist O, Santos LA, De Luca F, Jaramillo D.   +3 more
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

The G protein-coupled receptor ADGRG6 maintains mouse growth plate homeostasis through IHH signaling. [PDF]

J Bone Miner Res
Bian F, Hansen V, Feng HC, He J, Chen Y, Feng K, Ebrahimi B, Gray RS, Chai Y, Wu CL, Liu Z.   +10 more
europepmc   +1 more source

Gymnasts' wrist: distal radius growth plate injury

, 2009
Brent Messick, Kevin Burroughs
openalex   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

MiR-322-5p is involved in regulating chondrocyte proliferation and differentiation in offspring's growth plate of maternal gestational diabetes. [PDF]

Sci Rep
Qian F, Chen X, Wang S, Zhong Y, Liu M, Wang G, Yang X, Cheng X.   +7 more
europepmc   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Normal Bone Matrix Mineralization but Altered Growth Plate Morphology in the Lmna^G609G/G609G Mouse Model of Progeria. [PDF]

Aging Dis
Blouin S, Hartmann MA, Fratzl-Zelman N, Messmer P, Whisenant D, Erdos MR, Collins FS, Eriksson M, Strandgren C, Cabral WA, Dechat T.   +10 more
europepmc   +1 more source

SOX9 Governs Differentiation Stage-Specific Gene Expression in Growth Plate Chondrocytes via Direct Concomitant Transactivation and Repression

, 2011
Vyl Leung, Bo Gao, Keith K. H. Leung, Ian G. Melhado, Sarah Wynn, Tiffany Y. K. Au, Nelson W. F. Dung, James Y. B. Lau, Angel C. Y. Mak, Danny Chan, Kathryn S.E. Cheah   +10 more
openalex   +2 more sources

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte, Lucy Norcliffe‐Kaufmann, Maria Luisa Cotrina, Zenith Khan, Kaia Dalamo, Patricio Millar Vernetti, Matthew Lawless, Elisabetta Morini, Monica Salani, Marla Weetall, Jana Narasimhan, Agostino G. Rocha, Susan A. Slaugenhaupt, Horacio Kaufmann   +13 more
wiley   +1 more source