Results 41 to 50 of about 701,195 (269)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Mepiquat chloride-driven regulation in cotton in China: a review of physiological mechanisms, agronomic integration, and future trajectories

Journal of Cotton Research
Crop chemical regulation using plant growth regulators (PGRs) represents a key strategy for achieving high-efficiency cotton production in China. This review synthesizes four decades of research on mepiquat chloride (MC), an inhibitory PGR pivotal to ...
Xinyao Liu, Yao Wang, Mingwei Du, Fangjun Li, Xiaoli Tian, Zhaohu Li   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Regulation of Growth of Fibroblasts

Journal of Investigative Dermatology, 1978
Present knowledge on regulation of fibroblast growth is based on in vitro culture of fibroblasts from different sources. The research has focused on 2 problems: identification of the signal that reaches the fibroblast from outside and tells it to grow and identification of metabolic reactions inside the cell that commit it to initiate DNA synthesis ...
Ristow, Hans-Jürgen, Holley, Robert W, Messmer, Trudy O   +2 more
openaire   +2 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Characterizing Cotton Defoliation Progress via UAV-Based Multispectral-Derived Leaf Area Index and Analysis of Influencing Factors

Remote Sensing
Timely monitoring of cotton defoliation progress is crucial for optimizing the quality of mechanical harvesting. To accurately assess the defoliation status prior to mechanical picking, a field experiment was conducted in Hejian, Hebei Province, China ...
Yukun Wang, Zhenwang Zhang, Chenyu Xiao, Te Zhang, Keke Yu, Chong Zhang, Qinghua Liao, Fangjun Li, Sumei Wan, Guodong Chen, Xiaoli Tian, Mingwei Du, Zhaohu Li   +12 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Morphological and physiological mechanisms underlying lodging in cotton stems

Journal of Cotton Research
Background Cotton lodging has become increasingly prevalent due to extreme environmental conditions and agronomic practices, severely compromising yield, fiber quality, and mechanical harvesting efficiency.
Xinghua Yu, Mingyan Zhou, Weiming Chen, Yukun Wang, Haiyang Lu, Fangyong Wang, Mingwei Du, Huanyong Han, Xiaoli Tian, Zhaohu Li   +9 more
doaj   +1 more source

High nitrogen use efficiency in wheat is explained by a longer fast-increase period and adequate pre-anthesis nitrogen accumulation

Frontiers in Plant Science
IntroductionNitrogen (N)-efficient wheat cultivars achieve higher grain yields with equivalent N fertilizer inputs, and the grain filling character largely determines grain weight (GW) in cereal crops.
Minglong Yu, Churong Liu, Churong Liu, Hongrun Liu, Yushi Zhang, Zhaohu Li, Mingcai Zhang   +6 more
doaj   +1 more source