Results 121 to 130 of about 946,244 (261)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Synergistic effects of plant growth regulators and fe₃o₄ nanoparticles on in vitro organogenesis and bioactive compound production in hypericum perforatum. [PDF]

BMC Plant Biol
Al Nooh KM, Salim AM, Faizy WS, Dargiri SA, Meftahizade H.   +4 more
europepmc   +1 more source

Flowering induction in cassava using photoperiod extension premature pruning and plant growth regulators. [PDF]

PLoS One, 2023
Santos AD, Bandeira E Sousa M, Cunha Alves AA, de Oliveira EJ.   +3 more
europepmc   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Tillage management practices in combination of plant growth regulators to improve root growth, lodging characteristics and maize productivity under semi-arid regions. [PDF]

Sci Rep
Zhang H, Ali S, Kong R, Liu H, Lu H, Tian X, Rong F, Assal ME, Shaik MR, Sajid M.   +9 more
europepmc   +1 more source

Role of Hepatocyte Growth Regulators in Liver Regeneration. [PDF]

Cells, 2023
Kimura M, Moteki H, Ogihara M.
europepmc   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Discovery and Biological Evaluation of 3‑(1,2,3-Thiadiazol-5-yl)-1-arylimidazolidine-2,4-diones as Potential Plant Growth Regulators. [PDF]

ACS Omega
Kalinina TA, Evchik VS, Obydennov KL, Slepukhin PA, Kanwugu ON, Cherepanova OE, Glukhareva TV.   +6 more
europepmc   +1 more source

Optimization of Plant Growth Regulators for In Vitro Mass Propagation of a Disease-Free 'Shine Muscat' Grapevine Cultivar. [PDF]

Curr Issues Mol Biol, 2023
Kim SH, Zebro M, Jang DC, Sim JE, Park HK, Kim KY, Bae HM, Tilahun S, Park SM.   +8 more
europepmc   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source