Effect of Thionation of the Carbonyl Groups in Naphthalimide-Phenoxazine Electron Donor-Acceptor Dyads on the Excited- State Dynamics: Transient Optical and Electron Paramagnetic Resonance Spectral Studies. [PDF]
ChemistryThionation: Enhanced SOC and Unusually Large ZFS Parameters: Thionated electron donor–acceptor dyads based on naphthalimide (NI) and phenoxazine (PXZ) were prepared and the photophysical properties were studied. Fluorescence quenching and efficient intersystem crossing (ISC) were observed for the dyad with the NI unit thionated.
Zhang Y +7 more
europepmc +2 more sources
Stagonosporopsis cucurbitacearum Effector Protein ScAA9 Contributes to Virulence and Triggers Plant Immune Responses. [PDF]
Mol Plant PatholThe AA9 family protein ScAA9 of Stagonosporopsis cucurbitacearum plays dual roles as both a virulence factor for infection and a PAMP for host immune manipulation, highlighting the complexity of S. cucurbitacearum–host interactions. ABSTRACT Fungal pathogens secrete cell wall‐degrading enzymes that either act as virulence factors or are perceived by ...
Guo M, Lou J, Han S, Li D, Song F.
europepmc +2 more sources
The BDNF Loop 4 Dipeptide Mimetic Bis(N-monosuccinyl-L-seryl-L-lysine)hexamethylenediamide Is Active in a Depression Model in Mice after Acute Oral Administration [PDF]
, 2019 Low-molecular mimetic BDNF GSB-106, which is a substituted dimeric dipeptide, bis(N-monosuccinyl-L-seryl-L-lysine) hexamethylenediamide, was designed and synthesized in the V. V. Zakusov Research Institute of Pharmacology.
Antipova, Tatiana A. +7 more
core +1 more source
Новый глипролин ГЗК-111 с нейропсихотропной активностью [PDF]
, 2022 Thе article represents a review of our own researches, which describes the design, synthesis and pharmacological properties of linear substituted glyproline GZK-111, a potential drug for the complex treatment of psychiatric pathologies, including anxiety,
A. G. Alyaeva +5 more
core +4 more sources
Journal of Volgograd State Medical University, 2020 The technique of identification and quantitative determination definition of residual organic solvents in the original substance synthesized in FSBSI «Research Institute of Pharmacology named after V.V. Zakusov» on the basis of structure of the fourth loop of BDNF (GSB-106) is developed using method of gas-liquid chromatography (GLC) with static vapor ...
M. E Dudenkova +6 more
openaire +1 more source
, 2021 Major depression is a severe and prevalent brain disorder with a high disability burden, hence the push for effective treatments. Antidepressants have been around since the 1950s, and although current medications are much more effective than early ones ...
core +1 more source
Neurotrophic Activity and Its Modulation by Zinc Ion of a Dimeric Peptide Mimicking the Brain-Derived Neurotrophic Factor N-Terminal Region [PDF]
, 2022 Brain-derived neurotrophic factor (BDNF) is a neurotrophin (NT) essential for neuronal development and synaptic plasticity. Dysregulation of BDNF signaling is implicated in different neurological disorders.
Calvello, Mariantonietta +15 more
core +2 more sources
Mixotrophic growth under micro-oxic conditions in the purple sulfur bacterium "Thiodictyon syntrophicum" [PDF]
, 2019 The microbial ecosystem of the meromictic Lake Cadagno (Ticino, Swiss Alps) has been studied intensively in order to understand structure and functioning of the anoxygenic phototrophic sulfur bacteria community living in the chemocline. It has been found
Danza, Francesco +6 more
core +4 more sources
From micro to macro:unravelling the underlying mechanisms of Transcranial Magnetic Stimulation (TMS) [PDF]
, 2021 This PhD research investigated the underlying mechanisms of transcranial magnetic stimulation (TMS). TMS is a form of non-invasive brain stimulation, which is used both in research to alter brain activity and in the clinic where it is a treatment option ...
Thomson, Alix Charlotte
core +2 more sources
Angewandte Chemie, Volume 138, Issue 13, 23 March 2026.A needle‐shaped gold nanocluster, Au42(PET)32, serves as a powerful triplet sensitizer, enabling rubrene to fully express its intrinsic annihilator capability (spin statistical factor f = 0.58). This sensitizer–annihilator pair achieves record‐high upconversion internal quantum yields of 21.4% (808 nm excitation) and 15.0% (936 nm excitation ...
Masaaki Mitsui +2 more
wiley +2 more sources