Results 251 to 260 of about 269,348 (283)
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Biochimica et Biophysica Acta (BBA) - General Subjects, 1975
1. Two automated colorimetric methods have been developed for assaying the GSH and total thiol in protein-free extracts of erythrocytes. They employ as chromogens 5,5'-dithiobis-(2-nitrobenzoate) (DTNB) and alloxan. 2. The concentrations of GSH, GSSG and total non-protein thiol have been estimated in high and low GSH erythrocytes from Finnish Landrace ...
J D, Young, I A, Nimmo, J G, Hall
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1. Two automated colorimetric methods have been developed for assaying the GSH and total thiol in protein-free extracts of erythrocytes. They employ as chromogens 5,5'-dithiobis-(2-nitrobenzoate) (DTNB) and alloxan. 2. The concentrations of GSH, GSSG and total non-protein thiol have been estimated in high and low GSH erythrocytes from Finnish Landrace ...
J D, Young, I A, Nimmo, J G, Hall
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GSH and analogs in antiviral therapy
Molecular Aspects of Medicine, 2009Reduced glutathione (GSH) is the most prevalent non-protein thiol in animal cells. Its de novo and salvage synthesis serves to maintain a reduced cellular environment. GSH is the most powerful intracellular antioxidant and plays a role in the detoxification of a variety of electrophilic compounds and peroxides via catalysis by glutathione-S ...
Alessandra Fraternale +6 more
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Archives of Pediatrics & Adolescent Medicine, 1968
To the Editor .—Recently Krasner and Yaffe 1 reported observations on the development of GSH aryl-transferase activity in mouse liver during the neonatal period. They also tried to enhance such enzymatic activity in the newborn mouse by injecting phenobarbital and substrate (sulfobromophthalein [BSP]) into the mother at the end of the pregnancy ...
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To the Editor .—Recently Krasner and Yaffe 1 reported observations on the development of GSH aryl-transferase activity in mouse liver during the neonatal period. They also tried to enhance such enzymatic activity in the newborn mouse by injecting phenobarbital and substrate (sulfobromophthalein [BSP]) into the mother at the end of the pregnancy ...
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Xenobiotic Detoxification by GSH-Loaded Erythrocytes
1992It is well known that the cells of higher organisms are able to excrete unwanted foreign chemicals (pesticides, herbicides, aromatic amines used in the dye industries, etc.) after metabolic conversion. An important role in this process is performed by reduced glutathione (GSH) which is present at high concentrations (2mM) in all living cells.
A. FAZI +4 more
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GSH transporters: molecular characterization and role in GSH homeostasis.
Biological chemistry Hoppe-Seyler, 1996Considerable progress has been made in the last few years in the molecular identification and characterization of hepatic GSH transporter-associated polypeptides. We are now poised to determine their precise mechanisms of action and regulation at the transcriptional and post-translational level. It is also anticipated that molecular characterization of
N, Kaplowitz +5 more
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2010
Loss of dopaminergic neurons, oxidative stress, deficient bioenergetics and decreased levels of reduced glutathione (GSH) in the substantia nigra are biochemical hallmarks of idiopathic Parkinson’s disease (PD). The intent of this study was to test the hypothesis that disturbances in GSH and dopamine (DA) homeostasis are detrimental to dopaminergic ...
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Loss of dopaminergic neurons, oxidative stress, deficient bioenergetics and decreased levels of reduced glutathione (GSH) in the substantia nigra are biochemical hallmarks of idiopathic Parkinson’s disease (PD). The intent of this study was to test the hypothesis that disturbances in GSH and dopamine (DA) homeostasis are detrimental to dopaminergic ...
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1,3-Dinitrobenzene Metabolism and GSH Depletion
Chemical Research in Toxicology, 2002Previous work demonstrated that the mitochondrial fraction of rat seminiferous tubules is capable of metabolizing 1,3-dinitrobenzene, using NADPH as a cofactor. Moreover, 1,3-dinitrobenzene treatment of rat tubules caused a decrease in mitochondrial GSH levels.
Ian T, Reeve +2 more
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The Leading Edge, 2013
Organizers of geoscience meetings have a difficult job because choosing a specific, narrow topic important to the petroleum industry, specifically to the E&P portion of the petroleum industry, is not a trivial task. What interests some may not interest others. Co-organizers argue in favor of one topic and then another.
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Organizers of geoscience meetings have a difficult job because choosing a specific, narrow topic important to the petroleum industry, specifically to the E&P portion of the petroleum industry, is not a trivial task. What interests some may not interest others. Co-organizers argue in favor of one topic and then another.
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Uptake of dehydroascorbic acid in high-GSH and normal-GSH dog erythrocytes
Comparative Clinical Pathology, 2005Uptake of dehydroascorbic acid (DHA) was studied in two types of dog erythrocytes with high GSH and normal GSH levels. Compared with ascorbic acid uptake, DHA produced a much greater ascorbic acid accumulation in dog erythrocytes. Both dog erythrocytes showed a concentration dependence of DHA uptake, and cellular ascorbic acid concentrations were ...
Eri Ogawa +3 more
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Neuroscience Letters, 2011
To test whether copper exposure affects astroglial glutathione (GSH) metabolism, we have exposed astrocyte-rich primary cultures with copper chloride in concentrations of up to 30 μM and investigated cellular and extracellular GSH contents. Cultured astrocytes accumulated copper in a concentration-dependent manner thereby increasing the specific ...
Ivo F, Scheiber, Ralf, Dringen
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To test whether copper exposure affects astroglial glutathione (GSH) metabolism, we have exposed astrocyte-rich primary cultures with copper chloride in concentrations of up to 30 μM and investigated cellular and extracellular GSH contents. Cultured astrocytes accumulated copper in a concentration-dependent manner thereby increasing the specific ...
Ivo F, Scheiber, Ralf, Dringen
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