Results 261 to 270 of about 273,251 (302)
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1,3-Dinitrobenzene Metabolism and GSH Depletion

Chemical Research in Toxicology, 2002
Previous work demonstrated that the mitochondrial fraction of rat seminiferous tubules is capable of metabolizing 1,3-dinitrobenzene, using NADPH as a cofactor. Moreover, 1,3-dinitrobenzene treatment of rat tubules caused a decrease in mitochondrial GSH levels.
Ian T, Reeve   +2 more
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The GSH Spring Symposium

The Leading Edge, 2013
Organizers of geoscience meetings have a difficult job because choosing a specific, narrow topic important to the petroleum industry, specifically to the E&P portion of the petroleum industry, is not a trivial task. What interests some may not interest others. Co-organizers argue in favor of one topic and then another.
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Uptake of dehydroascorbic acid in high-GSH and normal-GSH dog erythrocytes

Comparative Clinical Pathology, 2005
Uptake of dehydroascorbic acid (DHA) was studied in two types of dog erythrocytes with high GSH and normal GSH levels. Compared with ascorbic acid uptake, DHA produced a much greater ascorbic acid accumulation in dog erythrocytes. Both dog erythrocytes showed a concentration dependence of DHA uptake, and cellular ascorbic acid concentrations were ...
Eri Ogawa   +3 more
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Copper-treatment increases the cellular GSH content and accelerates GSH export from cultured rat astrocytes

Neuroscience Letters, 2011
To test whether copper exposure affects astroglial glutathione (GSH) metabolism, we have exposed astrocyte-rich primary cultures with copper chloride in concentrations of up to 30 μM and investigated cellular and extracellular GSH contents. Cultured astrocytes accumulated copper in a concentration-dependent manner thereby increasing the specific ...
Ivo F, Scheiber, Ralf, Dringen
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GSH CONJUGATING ENZYME-Reply

Archives of Pediatrics & Adolescent Medicine, 1968
To the Editor .—The comments by Drs. Di Toro, Ansanelli, and Lupi are most pertinent and interesting. They complement and confirm our results and we would like to express our appreciation for their comments The effects of other pharmacologic agents on sulfobromophthalein (BSP) metabolism should be interpreted with some caution because the effect may ...
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Distribution of GSH and GSH cycle enzymes in black sea bass (Centropristis striata)

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1985
Abstract 1. 1. Tissue extracts were prepared from black sea bass kidney, liver, brain, red blood cells and muscle; each of the extracts was analyzed for the following glutathione (GSH)-dependent enzyme activities: Se-dependent and Se-independent GSH-peroxidases, GSH reductase, γ-glutamyl cysteine synthetase, GSH-S-transferase and γ-glutamyl ...
S.A. Braddon   +2 more
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GSH poisoning

The Journal of Emergency Medicine, 2005
Michael J, Matteucci, Richard F, Clark
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Human GSH-Transferase in Risk Assessment

1996
Human cytosolic glutathione-S-transferases (GST) are dimeric enzymes which have been classified, mainly by their isoelectric points, into four classes (Brockmoller et al. 1993): class α (basic, GSTA); class μ (near-neutral, new GSTM); class π (acidic, GSTP); class θ (slightly basic, GSTT).
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Cellular Gsh Metabolism During Hypoxia

1990
In recent years, we have studied the effect of hypoxia on hepatic GSH homeostasis. O2 dependence of GSH synthesis was studied in cells under different steady-state O2 with met or cys as precursor amino acids. GSH synthetic rate with met decreased from 0.71 to (J.16 nmol/106 cells/min under aerobic and anaerobic conditions, respectively.
Tak Yee Aw   +3 more
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Glutathione (GSH) Synthesis and Metabolism

2011
The tripeptide glutathione (GSH) is present in brain cells in millimolar concentrations. GSH has many important cellular and extracellular functions, of which the detoxification of reactive oxygen species and of xenobiotics are especially important. In the brain, astrocytes play a central role in the GSH metabolism.
Maike M. Schmidt, Ralf Dringen
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