SUPORTE HEMOTERÁPICO EM TALASSEMIA – EXPERIÊNCIA DE UM SERVIÇO DE HEMOTERAPIA PRIVADO
Hematology, Transfusion and Cell Therapy, 2023 Introdução: As Talassemias constituem um grupo heterogêneo de doenças geneticamente determinadas, que se caracterizam por defeito na síntese de uma ou mais cadeias polipeptídicas da hemoglobina.
PG Moura +8 more
doaj +1 more source
Glutathione Metabolism and the Novel Role of Mitochondrial GSH in Retinal Degeneration
Antioxidants, 2021 Glutathione (GSH) is present ubiquitously, and its role as a crucial cellular antioxidant in tissues, including the retina, is well established. GSH’s antioxidant function arises from its ability to scavenge reactive oxygen species or to serve as an ...
P. Sreekumar, D. Ferrington, R. Kannan
semanticscholar +1 more source
Glutathione increase by the n-butanoyl glutathione derivative (GSH-C4) inhibits viral replication and induces a predominant Th1 immune profile in old mice infected with influenza virus [PDF]
, 2019 During aging, glutathione (GSH) content declines and the immune system undergoes a deficiency in the induction of Th1 response. Reduced secretion of Th1 cytokines, which is associated with GSH depletion, could weaken the host defenses against viral ...
Amatore, D +9 more
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Expression of Heterologous OsDHAR Gene Improves Glutathione (GSH)-Dependent Antioxidant System and Maintenance of Cellular Redox Status in Synechococcus elongatus PCC 7942. [PDF]
, 2020 An excess of reactive oxygen species (ROS) can cause severe oxidative damage to cellular components in photosynthetic cells. Antioxidant systems, such as the glutathione (GSH) pools, regulate redox status in cells to guard against such damage ...
Beld, Joris +9 more
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GSH rescue by N-acetylcysteine [PDF]
Klinische Wochenschrift, 1991 Reduced glutathione (GSH) is the main intracellular low molecular weight thiol. GSH acts as a nucleophilic scavenger and as an enzyme-catalyzed antioxidant in the event of electrophilic/oxidative tissue injury. Therefore, GSH has a major role as a protector of biological structures and functions.
Ruffmann, R., Wendel, A.
openaire +2 more sources
RECUPERAÇÃO DE SANGUE INTRAOPERATÓRIO EM CIRURGIAS DE COLUNA VERTEBRAL
Hematology, Transfusion and Cell Therapy, 2023 As cirurgias da coluna, particularmente a cirurgia de correção de deformidades, podem resultar em grande perda de sangue devido aos longos tempos operatórios, extenso desgaste muscular e grandes superfícies de feridas envolvidas.A perda de sangue e a ...
SD Vieira +7 more
doaj +1 more source
Cellular glutathione content in the organ of Corti and its role during ototoxicity. [PDF]
, 2015 Glutathione (GSH) is the major scavenger of reactive oxygen species (ROS) inside cells. We used live confocal imaging in order to clarify the role of GSH in the biology of the organ of Corti, the sensory epithelium of the cochlea, before, during and ...
Duchen, MR, Gale, JE, Majumder, P
core +1 more source
ESTRUTURAÇÃO E IMPLANTAÇÃO DO COMITÊ DE INVESTIGAÇÃO E ANÁLISE DE EVENTOS (CIAE)
Hematology, Transfusion and Cell Therapy, 2023 Introdução: Corroborando com a prática de notificações de incidentes, o qual o grupo mantem uma excelente adesão, e compactuando com o princípio da melhoria contínua, base do nosso DNA institucional, no ano de 2022 foi instituído o Comitê de ...
LFF Dalmazzo +8 more
doaj +1 more source
Glutathione Metabolism in Renal Cell Carcinoma Progression and Implications for Therapies [PDF]
, 2019 A significantly increased level of the reactive oxygen species (ROS) scavenger glutathione (GSH) has been identified as a hallmark of renal cell carcinoma (RCC). The proposed mechanism for increased GSH levels is to counteract damaging ROS to sustain the
Meierhofer, David, Xiao, Yi
core +2 more sources
Glutathione treatment protects the rat liver against injury after warm ischemia and Kupffer cell activation [PDF]
, 2002 Background/Aim: The generation of reactive oxygen species by activated Kupffer cells (KC) may contribute to reperfusion injury of the liver during liver transplantation or resection.
Baron, A. +5 more
core +1 more source