Glutathione treatment protects the rat liver against injury after warm ischemia and Kupffer cell activation [PDF]
, 2002 Background/Aim: The generation of reactive oxygen species by activated Kupffer cells (KC) may contribute to reperfusion injury of the liver during liver transplantation or resection.
Baron, A. +5 more
core +1 more source
Glutathione Metabolism in Renal Cell Carcinoma Progression and Implications for Therapies [PDF]
, 2019 A significantly increased level of the reactive oxygen species (ROS) scavenger glutathione (GSH) has been identified as a hallmark of renal cell carcinoma (RCC). The proposed mechanism for increased GSH levels is to counteract damaging ROS to sustain the
Meierhofer, David, Xiao, Yi
core +2 more sources
Decreased glutathione biosynthesis contributes to EGFR T790M-driven erlotinib resistance in non-small cell lung cancer [PDF]
, 2016 Epidermal growth factor receptor (EGFR) inhibitors such as erlotinib are novel effective agents in the treatment of EGFR-driven lung cancer, but their clinical impact is often impaired by acquired drug resistance through the secondary T790M EGFR mutation.
Chater, E +13 more
core +2 more sources
Hematology, Transfusion and Cell Therapy, 2023 Introdução: Os serviços de hemoterapia possuem o desafio de manter um nível de estoque seguro de hemocomponentes de acordo com demandas transfusionais, garantindo que os pacientes sejam atendimentos de forma segura e eficaz. Os sistemas sanguíneos Rh (D,
BCA Alencar +4 more
doaj +1 more source
Extracellular free water and glutathione in first-episode psychosis-a multimodal investigation of an inflammatory model for psychosis. [PDF]
, 2021 Evidence has been accumulating for an immune-based component to the etiology of psychotic disorders. Advancements in diffusion magnetic resonance imaging (MRI) have enabled estimation of extracellular free water (FW), a putative biomarker of ...
Carter, Cameron S +7 more
core
Glutathione (GSH) and the GSH synthesis gene Gclm modulate vascular reactivity in mice [PDF]
Free Radical Biology and Medicine, 2012 Oxidative stress has been implicated in the development of vascular disease and in the promotion of endothelial dysfunction via the reduction in bioavailable nitric oxide (NO()). Glutathione (GSH) is a tripeptide thiol antioxidant that is utilized by glutathione peroxidase (GPx) to scavenge reactive oxygen species such as hydrogen peroxide and ...
Chad S, Weldy +9 more
openaire +2 more sources
AVALIAÇÃO DAS REAÇÕES ADVERSAS À DOAÇÃO DE SANGUE EM UM SERVIÇO PRIVADO DE SAÚDE
Hematology, Transfusion and Cell Therapy, 2023 Objetivos: Descrever as principais reações adversas relacionadas à doação de sangue, assim como identificar o perfil do doador e elencar as características do doador de sangue que podem favorecer estes eventos.
EAS Moraes +4 more
doaj +1 more source
Hematology, Transfusion and Cell Therapy, 2023 Introdução: De acordo com ministério da saúde, o serviço de hemoterapia deve realizar os seguintes exames imuno-hematológicos para qualificação do sangue do doador, a fim de garantir a eficácia terapêutica e a segurança da futura doação: tipagem ABO ...
ALG Amaral +4 more
doaj +1 more source
GSH Attenuates Organ Injury and Improves Function after Transplantation of Fatty Livers [PDF]
, 2010 Ischemia-reperfusion injury (IRI) is increased after transplantation of steatotic livers. Since those livers are increasingly used for transplantation, protective strategies must be developed. Reactive oxygen species (ROS) play a key role in hepatic IRI.
Angele, M. K. +7 more
core +1 more source
PERFIL DE ATENDIMENTO DE PACIENTES TRANSFUNDIDOS EM SERVIÇOS DE OBSTETRÍCIA EM SÃO PAULO
Hematology, Transfusion and Cell Therapy, 2023 Objetivos: Caracterizar o perfil de atendimento transfusional em serviços de obstetrícia de três Hospitais da cidade de São Paulo. Material e métodos: Estudo descritivo e retrospectivo realizado através da revisão de prontuários de puérperas ...
KJD Olio +6 more
doaj +1 more source