Results 141 to 150 of about 16,343,665 (315)

GSK-3 turns p53 deadly [PDF]

Cell Cycle, 2011
Charvet, Céline, Maurer, Ulrich
openaire   +4 more sources

Naphthoquinone as a New Chemical Scaffold for Leishmanicidal Inhibitors of Leishmania GSK-3. [PDF]

Biomedicines, 2022
Sebastián-Pérez V, Martínez de Iturrate P, Nácher-Vázquez M, Nóvoa L, Pérez C, Campillo NE, Gil C, Rivas L.   +7 more
europepmc   +1 more source

Clinical impact of multiparametric contrast‐enhanced dual‐energy computed tomography in arthritis imaging – a prospective single‐center study

Arthritis &Rheumatology, Accepted Article.
Objectives To evaluate the influence of contrast‐enhanced dual‐energy CT (CE‐DECT) in detecting and differentiating rheumatic joint diseases of the hand. Methods In this prospective study, patients with suspected arthritis of the hand were investigated consecutively alongside the standard clinical procedure.
Sevtap Tugce Ulas, Jürgen Mews, Sarah Ohrndorf, Robert Biesen, Katharina Ziegeler, Edgar Wiebe, Fabian Proft, Udo Schneider, Denis Poddubnyy, Torsten Diekhoff   +9 more
wiley   +1 more source

Gsk-3-Mediated Proteasomal Degradation of ATF4 Is a Proapoptotic Mechanism in Mouse Pancreatic β-Cells. [PDF]

Int J Mol Sci, 2022
Nagao Y, Amo-Shiinoki K, Nakabayashi H, Hatanaka M, Kondo M, Matsunaga K, Emoto M, Okuya S, Tanizawa Y, Tanabe K.   +9 more
europepmc   +1 more source

PS1 activates PI3K thus inhibiting GSK-3 activity and tau overphosphorylation: effects of FAD mutations [PDF]

, 2004
Lia Baki, Junichi Shioi, Paul H. Wen, Zhiping Shao, A. L. Schwarzman, Miguel A. Gama-Sosa, Rachael L. Neve, Nikolaos K. Robakis   +7 more
openalex   +1 more source

GSK-3: tricks of the trade for a multi-tasking kinase

Journal of Cell Science, 2003
B. Doble, J. Woodgett
semanticscholar   +1 more source

Clonal sharing of CD8+ T‐cells links skin and joint inflammation in psoriatic arthritis

Arthritis &Rheumatology, Accepted Article.
Objective Psoriatic arthritis (PsA) is an HLA class I‐associated inflammatory arthritis that develops in up to 30% of people with psoriasis. We tested the hypothesis that skin and joint inflammation in PsA is linked in terms of CD8+ T‐cell phenotype and clonality.
Lucy E. Durham, Frances Humby, Nora Ng, Roman Laddach, Elizabeth H. Gray, Sarah E. Ryan, Kathryn J.A. Steel, Rosie Ross, Giovanni A. M. Povoleri, Rosamond Nuamah, Kathy Fung, Athul Menon Kallayil, Pawan Dhami, Bruce W. Kirkham, Leonie S. Taams   +14 more
wiley   +1 more source

Prospects in GSK-3 Signaling: From Cellular Regulation to Disease Therapy. [PDF]

Cells, 2022
Arciniegas Ruiz S, Rippin I, Eldar-Finkelman H.   +2 more
europepmc   +1 more source

Identification of Nonsteroidal Anti-inflammatory Drug-activated Gene (NAG-1) as a Novel Downstream Target of Phosphatidylinositol 3-Kinase/AKT/GSK-3β Pathway [PDF]

, 2004
Kiyoshi Yamaguchi, Seong‐Ho Lee, Thomas E. Eling, Seung Joon Baek   +3 more
openalex   +1 more source

First‐in‐human safety, tolerability, pharmacokinetics and pilot food‐effect study of the candidate antimalarial compound MMV367

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim To evaluate the safety, tolerability and pharmacokinetics in healthy participants of orally administered MMV367 (GSK3772701), a novel antimalarial interfering with Plasmodium falciparum acyl coenzyme A synthetase 10/11 function. Methods This first‐in‐human study enrolled 47 healthy male and female participants.
Andrea Kuemmerle, Nand Singh, Denis Gossen, Annick Janin, Raman Sharma, Anthony Cahn, Rachel A. Gibson, Somasekhara R. Menakuru, Erin Lambourne, Tom Dove, Francisco‐Javier Gamo, Laura Sanz, Benoit Bestgen, Stephan Chalon   +13 more
wiley   +1 more source