Results 231 to 240 of about 121,769 (336)

α-Synuclein Induces the GSK-3-Mediated Phosphorylation and Degradation of NURR1 and Loss of Dopaminergic Hallmarks. [PDF]

Mol Neurobiol, 2021
García-Yagüe ÁJ, Lastres-Becker I, Stefanis L, Vassilatis DK, Cuadrado A.   +4 more
europepmc   +1 more source

MAP4K4 and GSK-3 pathways complement DLK/LZK signaling to control cell death and axon degeneration in retinal ganglion cells

, 2019
Amit K. Patel, Katy L. Mitchell, Baranda S. Hansen, Cindy Berlinicke, Risa Broyer, Donald J. Zack, Derek S. Welsbie   +6 more
openalex   +1 more source

CCL21 Facilitates Chemoresistance and Cancer Stem Cell‐Like Properties of Colorectal Cancer Cells through AKT/GSK‐3β/Snail Signals [PDF]

, 2015
Linlin Lu, Xiaohong Chen, Ge Zhang, Zongcai Liu, Wu Nong, Hao Wang, Yifei Qi, Hongsheng Wang, Shao Hui Cai, Jun Du, Shao Hui Cai, Jun Du   +11 more
openalex   +1 more source

The cervico‐vaginal DNA methylation WID‐qEC test: An epigenetic marker associated with ovarian cancer in the absence of endometrial and cervical cancer

International Journal of Cancer, EarlyView.
What's New? The DNA methylation‐based WID‐qEC test has been validated for the accurate detection of endometrial and cervical cancers using cervico‐vaginal samples. However, a small proportion of women test positive despite the absence of these cancers. This study explored the associated biological and clinical characteristics to inform potential follow‐
Elisa Redl, Chiara Herzog, Charlotte Vavourakis, James Barrett, Allison Jones, Iona Evans, Daniel Reisel, Ranjit Manchanda, Line Bjørge, Michal Zikan, David Cibula, Twana Alkasalias, Angelique Flöter Rådestad, Kristina Gemzell‐Danielsson, Louis Dubeau, Nicola MacDonald, Davor Jurkovic, Nora Pashayan, Martin Widschwendter   +18 more
wiley   +1 more source

GSK-3 kinase a putative therapeutic target in trypanosomatid parasites. [PDF]

Braz J Infect Dis
Diaz AP, Canal CAM, Valdés AJ, Delgado JEG, Varela-M RE.   +4 more
europepmc   +1 more source

Deletion of Schizophrenia Susceptibility Gene Ulk4 Leads to Abnormal Cognitive Behaviors via Akt-GSK-3 Signaling Pathway in Mice. [PDF]

Schizophr Bull, 2022
Hu L, Zhou BY, Yang CP, Lu DY, Tao YC, Chen L, Zhang L, Su JH, Huang Y, Song NN, Chen JY, Zhao L, Chen Y, He CH, Wang YB, Lang B, Ding YQ.   +16 more
europepmc   +1 more source

GBP, an Inhibitor of GSK-3, Is Implicated in Xenopus Development and Oncogenesis [PDF]

, 1998
Cynthia Yost, Gist H. Farr, Sarah B. Pierce, Denise M. Ferkey, Michelle Mingzi Chen, David Kimelman   +5 more
openalex   +1 more source

Maternal RSV vaccination for infant protection: A systematic review and meta‐analysis of phase 3 trials with an integrated economic evaluation

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Respiratory syncytial virus (RSV) is a leading cause of hospitalization and mortality in early infancy. Maternal immunization offers a preventive strategy, but uncertainties regarding safety and economic value have limited its implementation.
Johnatan Torres‐Torres, Lourdes Rojas‐Zepeda, José Rafael Villafan‐Bernal, Raigam Martinez‐Portilla, Salvador Espino‐y‐Sosa, Pablo Cerda‐Flores, Elsa Romelia Moreno‐Verduzco, Irma Eloisa Monroy‐Muñoz, Ameyran Yolanda Gonzalez‐Guerrero, Juan Mario Solis‐Paredes, Javier Perez Duran   +10 more
wiley   +1 more source

Neurological Functions of the Masterswitch Protein Kinase – Gsk-3 [PDF]

Frontiers in Molecular Neuroscience, 2012
Oksana eKaidanovich-Beilin, Jean-Martin eBeaulieu, Richard Scott Jope, James Robert Woodgett, James Robert Woodgett   +4 more
openaire   +3 more sources

Using generalized quantitative structure–property relationship (QSPR) models to predict host cell protein retention in ion‐exchange chromatography

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Selecting an optimal chromatography resin during biopharmaceutical downstream process development is a great challenge. This is especially the case for recombinant subunit vaccines, where product properties vary greatly and recovery often involves cell lysis, which yields a complex mixture of different host cell materials. Host cell
Tim Neijenhuis, Olivier Le Bussy, Geoffroy Geldhof, Marieke E Klijn, Marcel Ottens   +4 more
wiley   +1 more source