Results 91 to 100 of about 46,501 (160)

Frontal Bone Insufficiency in Gsk3β Mutant Mice. [PDF]

, 2016
The development of the mammalian skull is a complex process that requires multiple tissue interactions and a balance of growth and differentiation. Disrupting this balance can lead to changes in the shape and size of skull bones, which can have serious ...
Wardati Yakob, Karen J Liu, Heather Szabo-Rogers, Yakob, Wardati, Liu, Karen J.; id_orcid, Szabo-Rogers, Heather   +5 more
core   +1 more source

Role of STRAP in regulating GSK3β function and Notch3 stabilization

, 2011
Glycogen synthase kinase 3β (GSK3β) can regulate a broad range of cellular processes in a variety of cell types and tissues through its ability to phosphorylate its substrates in a cell- and time-specific manner.
Pierre P. Massion, Zhang, Wanguang, Adriana L. Gonzalez, Gonzalez, Adriana L, Datta, Pran K, Pran K. Datta, Kashikar, Nilesh D, Nilesh D. Kashikar, Wanguang Zhang, Massion, Pierre P   +9 more
core   +1 more source

CDK5 activator protein p25 preferentially binds and activates GSK3β

, 2014
Glycogen synthase kinase 3β (GSK3β) and cyclin-dependent kinase 5 (CDK5) are tau kinases and have been proposed to contribute to the pathogenesis of Alzheimer's disease.
Herrup, Karl, Zhang, Guan Yun, Chow, Hei Man, Guo, Dong, Zhou, Jie Chao, Zhang, Jie, Li, Hui Fang   +6 more
core   +1 more source

Effect of 2-(phenylamino)-7,8-dihydroquinazolin-5(6H)-one derivatives on GSK3β and DYRK1A kinases for the multi-target treatment of neurodegenerative diseases

reservedIntroduzione. Negli organismi eucarioti, la fosforilazione delle proteine rappresenta una delle più comuni e importanti modifiche post-traduzionali.
CUNICO, KIM
core  

Association of MiRNA Polymorphisms Involved in the PI3K/ATK/GSK3β Pathway with T2DM in a Chinese Population

Pharmacogenomics and Personalized Medicine
Xing Zhou,1– 3,* Man Yang,1,* Ying Yang,1 Fan Xu,1 Feiying Wang,1 Ming Jiao,2,4 Wenyu Tao,1 Yiping Li1 1Department of Endocrinology, The Affiliated Hospital of Yunnan University & The Second People’s Hospital of Yunnan Province, Kunming, Yunnan ...
Zhou X, Yang M, Yang Y, Xu F, Wang F, Jiao M, Tao W, Li Y   +7 more
doaj  

Molecular cloning, expression and isolation of recombinant human GSK3β

, 2023
Glikogen sintaza kinaza 3 beta (GSK3β) je serin/treonin kinaza, ki ima vlogo pri številnih biokemijskih procesih in boleznih. Sestavljena je iz N-končne domene, bogate z β-trakovi, in C-končne α-vijačne domene. GSK3β kot del biomolekularnega kondenzata β-
Kovačić, Marko
core  

Phospho-GSK3β (Ser 9) contents in rhCCN2 stimulated hearts.

, 2016
Western blot analysis of phospho-GSK3β (Ser-9) contents in extracts of murine hearts following ex vivo perfusion of the hearts (Langendorff-perfusion) in the absence or presence of increasing concentrations of recombinant human CCN2.
Ole Jørgen Kaasbøll (292846), Ingvild Tronstad Moe (1804216), Mohammad Shakil Ahmed (1804210), Håvard Attramadal (224421), Else Marie Valbjørn Hagelin (1804213), Espen Stang (151359)   +5 more
core   +1 more source

GSK3β labeling in the hippocampus.

, 2013
A) Low magnification image showing GSK3β labeling in different layers of the hippocampus. This immunolabeling is especially robust in the Cornu Amonis (CA) subfields and in the dentate gyrus (DG).
Gautam N. Bijur (364319), Miguel Melendez-Ferro (367517), Rosalinda C. Roberts (367518), Emma Perez-Costas (367514), Johanna C. Gandy (367515)   +4 more
core   +1 more source

Aβ-Reelin fails to induce phosphorylation of Dab1 and GSK3β.

, 2013
Total cell lysates from primary mouse cortical neuron cultures treated without Reelin (No Reel) or with similar amounts of Reelin obtained from SH-SY5Y cells treated with 0 (control, C-Reel) or 10 µM of Aβ42 (Aβ-Reel) were probed with antibodies specific
Valeria Balmaceda (444653), Arancha Botella-López (444654), Javier Sáez-Valero (136855), Inmaculada Cuchillo-Ibáñez (444652), Jesus Avila (5655838), Alberto Rabano (3527426)   +5 more
core   +1 more source

The redox-sensitive GSK3β is a key regulator of glomerular podocyte injury in type 2 diabetic kidney disease

Redox Biology
Emerging evidence suggests that GSK3β, a redox-sensitive transducer downstream of insulin signaling, acts as a convergent point for myriad pathways implicated in kidney injury, repair, and regeneration.
Mengxuan Chen, Yudong Fang, Yan Ge, Shuhao Qiu, Lance Dworkin, Rujun Gong   +5 more
doaj   +1 more source