Results 71 to 80 of about 46,501 (160)
GSK3β regulates BMAL1 stability.
(A) HEK 293 cells were co-transfected with plasmids expressing Flag-myc-BMAL1, myc-CLOCK with or without CA-Akt. 48 hours post-transfection nuclear lysates were prepared and resolved by SDS-PAGE.
Emiliana Borrelli (221570) +4 more
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Original uncropped and unadjusted image for GSK3β.
Immunoblotting figures for GSK3β expression of muscle samples from Sham, Li, Gly and Gly+Li rats. (TIF)
Antonio Carlos Seguro (12731318) +6 more
core +2 more sources
GSK3β N-terminus binding to p53 promotes its acetylation [PDF]
The prevalence in human cancers of mutations in p53 exemplifies its crucial role as a tumor suppressor transcription factor. Previous studies have shown that the constitutively active serine/threonine kinase glycogen synthase kinase-3β (GSK3β) associates
Jope Richard S +5 more
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Variations in the Wnt/β-Catenin Pathway Key Genes as Predictors of Cervical Cancer Susceptibility
Bingqi Wang, Min Wang, Xianping Li, Min Yang, Lei Liu Department of Laboratory Medicine, The Second Xiangya Hospital, Central South University, Changsha 410011, Hunan, People’s Republic of ChinaCorrespondence: Min WangDepartment of Laboratory ...
Wang B, Wang M, Li X, Yang M, Liu L
doaj
High glucose-induced phosphorylation of GSK3β.
Endothelial cells were grown in serum-free medium containing normal glucose (NG, 5.5 mM) or high glucose (HG, 25 mM) with or without VEGFR inhibitor (VEGFRI) for 1 to 5 days.
Michael W. Brands (442972) +6 more
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In vivo regulation of glycogen synthase kinase 3β activity in neurons and brains
Glycogen synthase kinase 3β (GSK3β) is a multifunctional protein kinase involved in many cellular activities including development, differentiation and diseases.
Ambika Krishnankutty +9 more
doaj +1 more source
61 p.-11 fig. 2 tab.-5 fig. supl.Myotonic Dystrophy type 1 (DM1) is a multisystem neuro-muscular disease without cure. One of the possible therapeutic approaches for DM1 is correction of RNA-binding proteins, CUGBP1 and MBNL1, misregulated in DM1. CUGBP1
Weng, Wen-Chin +9 more
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GSK3β specificity and distribution in the cortex.
A) Immunoblot of mouse brain lysates showing the specificity of the antibody used. The left column shows the presence of 2 bands, an upper band (GSK3α) and a lower band (GSK3β), when there is no blocking peptide present (−).
Gautam N. Bijur (364319) +4 more
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Glycogen Synthase Kinase 3β in Cancer Biology and Treatment
Glycogen synthase kinase (GSK)3β is a multifunctional serine/threonine protein kinase with more than 100 substrates and interacting molecules. GSK3β is normally active in cells and negative regulation of GSK3β activity via phosphorylation of its serine 9
Takahiro Domoto +3 more
doaj +1 more source
Protein expression and phosphorylation of GSK3β:
A Total GSK3βprotein expression relative to β actin; B – Phosphorylated S9 GSK3βprotein (p-GSK3β) expression relative to β actin; C -Ratio of p-GSK3β to total GSK3β; D - Akt2 gene expression relative to GapDH.
Helene Cousin (280147) +7 more
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