Decoding the relationship between oxidative stress and antiseizure medications using network pharmacology and molecular docking [PDF]
Oxidative stress is known to be associated with epilepsy, and antiseizure medication treatment, albeit with limited consensus on the specific oxidative stress pathways/proteins involved. Identifying these can reveal novel therapeutic targets for epilepsy
Malhar Desai +7 more
doaj +2 more sources
ПОИСК 2-ОКСИНДОЛЬНЫХ ИНГИБИТОРОВ GSK3B С АНТИДИАБЕТИЧЕСКИМ ПОТЕНЦИАЛОМ
В.Г. Клочков +7 more
openalex +2 more sources
GSK3B inhibition partially reverses brain ethanol-induced transcriptomic changes in C57BL/6J mice: Expression network co-analysis with human genome-wide association studies [PDF]
Scott Gottlieb +4 more
openalex +2 more sources
Dynamic telomerase gene suppression via network effects of GSK3 inhibition [PDF]
<b>Background</b>: Telomerase controls telomere homeostasis and cell immortality and is a promising anti-cancer target, but few small molecule telomerase inhibitors have been developed. Reactivated transcription of the catalytic subunit hTERT
Bilsland, Alan E. +10 more
core +22 more sources
Impact of MiRNAs on Wnt-related gene activity in breast cancer [PDF]
Breast cancer is the most commonly diagnosed cancer in women. The Wnt pathway is involved in the regulation of cell proliferation, differentiation, survival, and migration.
Tomasz Sirek +14 more
doaj +2 more sources
Role of prefrontal cortex Gsk3b as a new therapeutic target for alcohol use disorder
Sam Gottlieb +3 more
openalex +2 more sources
Disrupted in schizophrenia 1 (DISC1); glycogen synthase kinase 3β (GSK3B) [PDF]
openalex +3 more sources
Numerous studies have considered galectin-3 or Glycogen synthase kinase 3 beta (GSK3B) as a potential prognosis marker for various cancers. However, the correlation between the protein expression of galectin-3/GSK3B and the clinical parameters of ...
Hung-Pei Tsai +6 more
doaj +1 more source
β-Catenin (CTNNB1); glycogen synthase kinase 3β (GSK3B) [PDF]
openalex +3 more sources

