Results 1 to 10 of about 386,929 (385)

GTP: Gatekeeper for Autophagy [PDF]

open access: yesMolecular Cell, 2010
Chaperone-mediated autophagy (CMA) is involved in cellular quality control, and in the response to stress, deterioration in CMA contributes to the aging phenotype and to various disorders. The paper by Bandyopadhyay et al. in this issue of Molecular Cell demonstrates the role of GTP binding by elongation factor 1 alpha (EF1alpha) in regulating the ...
Beau, Isabelle, Codogno, Patrice
openaire   +2 more sources

Synthesis and Effect of Conformationally Locked Carbocyclic Guanine Nucleotides on Dynamin

open access: yesBiomolecules, 2022
Guanine nucleotides can flip between a North and South conformation in the ribose moiety. To test the enzymatic activity of GTPases bound to nucleotides in the two conformations, we generated methanocarba guanine nucleotides in the North or South ...
Kiran S. Toti   +4 more
doaj   +1 more source

GTP-Yeast Actin [PDF]

open access: yesJournal of Biological Chemistry, 2002
Because of the apparently greater conformational flexibility of yeast versus muscle actin and the ability of other members in the actin protein superfamily to efficiently use both ATP and GTP, we assessed the ability of yeast actin to function with GTP.
Kuo-Kuang, Wen   +2 more
openaire   +2 more sources

Adaptive Interpolation Method for Generalized Triangular Prism (GTP) Geological Model Based on the Geometric Smoothness Rule

open access: yesFrontiers in Earth Science, 2022
Three dimensional (3D) geological model is frequently used to represent the geological conditions of the subsurface. The generalized triangular prism (GTP) model designed for borehole sampling data is a spatial data model that could retain the internal ...
Liming Sun   +5 more
doaj   +1 more source

Multidimensional assessment of Game Transfer Phenomena: Intrusive cognitions, perceptual distortions, hallucinations and dissociations

open access: yesFrontiers in Psychology, 2022
Game Transfer Phenomena (GTP) refers to a cluster of involuntary phenomena related to playing videogames, including sensory and cognitive intrusions, transient changes in perception and self-agency.
Angelica B. Ortiz de Gortari   +2 more
doaj   +1 more source

Cumulative Exposure to High γ-Glutamyl Transferase Level and Risk of Diabetes: A Nationwide Population-Based Study [PDF]

open access: yesEndocrinology and Metabolism, 2022
Background Elevated γ-glutamyl transferase (γ-GTP) level is associated with metabolic syndrome, impaired glucose tolerance, and insulin resistance, which are risk factors for type 2 diabetes. We aimed to investigate the association of cumulative exposure
Ji-Yeon Park   +6 more
doaj   +1 more source

An integrated approach to infer cross-talks between intracellular protein transport and signaling pathways

open access: yesBMC Bioinformatics, 2018
Background The endomembrane system, known as secretory pathway, is responsible for the synthesis and transport of protein molecules in cells. Therefore, genes involved in the secretory pathway are essential for the cellular development and function ...
Kumar Parijat Tripathi   +2 more
doaj   +1 more source

Green tea polyphenol-reduced graphene oxide: derivatisation, reduction efficiency, reduction mechanism and cytotoxicity [PDF]

open access: yes, 2014
This paper reports on the derivatisation, reduction efficiency, reduction mechanism and cytotoxicity of green tea polyphenol-reduced graphene oxide (GTP-RGO).
Abdullah, M. F.   +2 more
core   +1 more source

Cryo-EM of elongating ribosome with EF-Tu•GTP elucidates tRNA proofreading

open access: yesNature, 2020
Ribosomes accurately decode mRNA by proofreading each aminoacyl-tRNA that is delivered by the elongation factor EF-Tu 1 . To understand the molecular mechanism of this proofreading step it is necessary to visualize GTP-catalysed elongation, which has ...
A. Loveland, G. Demo, A. Korostelev
semanticscholar   +1 more source

Probiotic shelf life, antioxidant, sensory, physical and chemical properties of yogurts produced with lactobacillus acidophilus and green tea powder [PDF]

open access: yesKafkas Universitesi Veteriner Fakültesi Dergisi, 2019
The aim of the present study was to determine the effects of the addition of green tea powder (GTP) in the production of yogurt on survival of Lactobacillus acidophilus (P) and the yogurt properties. Four yogurt groups (yogurt without P and GTP, Control,
Songül ÇAKMAKÇI   +7 more
doaj   +1 more source

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