Results 141 to 150 of about 190,941 (249)

Pharmacological restoration of GTP hydrolysis by mutant RAS [PDF]

Antonio Cuevas-Navarro, Yasin Pourfarjam, Feng Hu, Diego J. Rodriguez, Alberto Vides, Ben Sang, Shijie Fan, Yehuda Goldgur, Elisa de Stanchina, Piro Lito   +9 more
openalex   +1 more source

Compartmentalisation in cAMP signalling: A phase separation perspective

British Journal of Pharmacology, EarlyView.
Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
wiley   +1 more source

M-Ras distinct activation scenarios: A mechanistic outlook and targeting. [PDF]

Comput Struct Biotechnol J
Xu L, Liu Y, Jang H, Nussinov R.
europepmc   +1 more source

Discovery of a New Prokaryotic Type I GTP Cyclohydrolase Family [PDF]

, 2006
Basma Yacoubi, Shilah A. Bonnett, Jessica N. Anderson, Manal A. Swairjo, Dirk Iwata‐Reuyl, Valérie de Crécy‐Lagard   +5 more
openalex   +1 more source

Non‐canonical PKG1 regulation in cardiovascular health and disease

British Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

Synthesis of 2'-fucosyllactose using multi-enzyme cascade with cofactor regeneration. [PDF]

Sci Rep
Cao C, Bai Y, Zhang M, Khan SS, Ji Y, Liu L.   +5 more
europepmc   +1 more source

Activation of GTP hydrolysis in mRNA-tRNA translocation by elongation factor G [PDF]

, 2015
Wen Li, Zheng Liu, Ravi Kiran Koripella, Robert Langlois, Suparna Sanyal, Joachim Frank   +5 more
openalex   +1 more source

The potential for biased signalling in the P2Y receptor family of GPCRs

British Journal of Pharmacology, EarlyView.
The purinergic receptor family is primarily activated by nucleotides, and contains members of both the G protein coupled‐receptor (GPCR) superfamily (P1 and P2Y) and ligand‐gated ion channels (P2X). The P2Y receptors are widely expressed in the human body, and given the ubiquitous nature of nucleotides, purinergic signalling is involved with a plethora
Claudia M. Sisk, Simon Pitchford, Graham Ladds   +2 more
wiley   +1 more source

Extensile Active Hydrogels Driven by Living FtsZ Polymers. [PDF]

Small
Kharbedia M, Herráez-Aguilar D, Calero M, López-Menendez H, Luque-Rioja C, Moleiro LH, Santos C, Lillo P, Monroy F.   +8 more
europepmc   +1 more source

Molecular cloning of Ian4: a BCR/ABL-induced gene that encodes an outer membrane mitochondrial protein with GTP-binding activity [PDF]

, 2001
Laurence Dahéron
openalex   +1 more source