Cumulative Exposure to High γ-Glutamyl Transferase Level and Risk of Diabetes: A Nationwide Population-Based Study [PDF]
Endocrinology and Metabolism, 2022 Background Elevated γ-glutamyl transferase (γ-GTP) level is associated with metabolic syndrome, impaired glucose tolerance, and insulin resistance, which are risk factors for type 2 diabetes. We aimed to investigate the association of cumulative exposure
Ji-Yeon Park +6 more
doaj +1 more source
BMC Bioinformatics, 2018 Background The endomembrane system, known as secretory pathway, is responsible for the synthesis and transport of protein molecules in cells. Therefore, genes involved in the secretory pathway are essential for the cellular development and function ...
Kumar Parijat Tripathi +2 more
doaj +1 more source
Green tea polyphenol-reduced graphene oxide: derivatisation, reduction efficiency, reduction mechanism and cytotoxicity [PDF]
, 2014 This paper reports on the derivatisation, reduction efficiency, reduction mechanism and cytotoxicity of green tea polyphenol-reduced graphene oxide (GTP-RGO).
Abdullah, M. F. +2 more
core +1 more source
Cryo-EM of elongating ribosome with EF-Tu•GTP elucidates tRNA proofreading
Nature, 2020 Ribosomes accurately decode mRNA by proofreading each aminoacyl-tRNA that is delivered by the elongation factor EF-Tu 1 . To understand the molecular mechanism of this proofreading step it is necessary to visualize GTP-catalysed elongation, which has ...
A. Loveland, G. Demo, A. Korostelev
semanticscholar +1 more source
The speed of GTP hydrolysis determines GTP cap size and controls microtubule stability
eLife, 2020 Microtubules are cytoskeletal polymers whose function depends on their property to switch between states of growth and shrinkage. Growing microtubules are thought to be stabilized by a GTP cap at their ends.
Johanna Roostalu +5 more
doaj +1 more source
The chloroplast import receptor Toc34 functions as preprotein-regulated GTPase [PDF]
, 2002 Toc34 is a protein of the chloroplast outer envelope membrane that acts as receptor for preproteins containing a transit sequence. The recognition of preproteins by Toc34 is regulated by GTP binding and phosphorylation.
Hörth, P. +5 more
core +1 more source
A guanosine 5′-triphosphate-dependent protein kinase is localized in the outer envelope membrane of pea chloroplasts [PDF]
, 1988 A guanosine 5-triphosphate (GTP)-dependent protein kinase was detected in preparations of outer chloroplast envelope membranes of pea (Pisum sativum L.) chloroplasts.
A.M. Edelman +34 more
core +1 more source
GTP Cyclohydrolase 1/Tetrahydrobiopterin Counteract Ferroptosis through Lipid Remodeling
ACS Central Science, 2019 Ferroptosis is an iron-dependent form of regulated cell death linking iron, lipid, and glutathione levels to degenerative processes and tumor suppression.
Vanessa A N Kraft +16 more
semanticscholar +1 more source
Reciprocal regulation of PKA and rac signaling [PDF]
, 2013 Activated G protein-coupled receptors (GPCRs) and receptor tyrosine kinases relay extracellular signals through spatial and temporal controlled kinase and GTPase entities.
A. Riml +47 more
core +1 more source
Analytical Chemistry, 2014 Thiopurine drugs are widely used as antileukemic drugs and immunosuppressive agents, and 6-thioguanosine triphosphate ((S)GTP) is a major metabolite for these drugs. Recent studies have suggested that thiopurine drugs may exert their cytotoxic effects partly through binding of (S)GTP to a GTP-binding protein, Rac1.
Debin Ji +3 more
openaire +3 more sources