Results 71 to 80 of about 386,929 (385)

Essential Role of the G-Domain in Targeting of the Protein Import Receptor atToc159 to the Chloroplast Outer Membrane [PDF]

, 2002
Two homologous GTP-bindin proteins, atToc33 and atToc159, control access of cytosolic precursor proteins to the chloroplast, at Toc33 is a constitutive outer chloroplast membrane protein, whereas the precusor receptor atToc159 may be able to switch ...
Alvarez-Huerta, Mayte, Bauer, Jörg, Hiltbrunner, Andreas, Kessler, Felix, Schnell, Danny J., Smith, Matthew D., Vidi, Pierre-Alexandre, Weibel, Petra   +7 more
core   +3 more sources

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Revisiting the microtubule based quantum models of mind: tubulin bound GTP cannot pump microtubule coherence or provide energy for alpha <-> beta computation in stable microtubules [PDF]

, 2003
The current paper investigates the biological models of stable brain microtubules as quantum or classical computers whose function is based on electron hopping associated with kinking of the tubulin dimer. Hameroff (1998a, 1998b, 2003a, 2003b), Tuszynski
Georgiev, Danko
core  

Parkinson’s disease in GTP cyclohydrolase 1 mutation carriers

Brain : a journal of neurology, 2014
Mutations in the gene encoding the dopamine-synthetic enzyme GTP cyclohydrolase-1 (GCH1) cause DOPA-responsive dystonia (DRD). Mencacci et al. demonstrate that GCH1 variants are associated with an increased risk of Parkinson's disease in both DRD ...
N. Mencacci, N. Mencacci, I. Isaias, M. Reich, Christos Ganos, Christos Ganos, V. Plagnol, J. Polke, J. Bras, J. Hersheson, Maria Stamelou, Maria Stamelou, A. Pittman, A. Noyce, K. Mok, T. Opladen, E. Kunstmann, Sybille Hodecker, A. Münchau, J. Volkmann, S. Samnick, K. Sidle, Tina Nanji, M. Sweeney, H. Houlden, A. Batla, A. Zecchinelli, G. Pezzoli, G. Marotta, A. Lees, P. Alegria, P. Krack, F. Cormier‐Dequaire, S. Lesage, A. Brice, P. Heutink, T. Gasser, S. Lubbe, H. Morris, P. Taba, S. Kõks, E. Majounie, J. R. Gibbs, A. Singleton, J. Hardy, S. Klebe, K. Bhatia, N. Wood   +47 more
semanticscholar   +1 more source

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

FEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti, Bruna Lopes Correia, Francielle Cristina Nakamura Manicardi, Nairana Mithieli de Queiroz Eskuarek Melo, Vanesa de Oliveira Pateis, Jurandir Fernando Comar, Anacharis Babeto de Sá‐Nakanishi, Adelar Bracht, Lívia Bracht   +8 more
wiley   +1 more source

Meat Quality, Intestinal Microbiology and Serum Biochemical Parameters of Broilers Fed Different Levels of Green Tea (Camellia sinensis) and Mulberry (Morus alba) Leaves Powder

Veterinary Medicine and Science
Background Today, customers pay more attention to the feed composition and carcasses of poultry, and the interest in using natural and safe compounds such as medicinal plants and their extracts in animal feed is increasing.
Fatemeh Aziz‐Aliabadi, Hadi Noruzi, Ahmad Hassanabadi   +2 more
doaj   +1 more source

Mitigation of oxidative damage by green tea polyphenols and Tai Chi exercise in postmenopausal women with osteopenia. [PDF]

PLoS ONE, 2012
Osteoporosis is a degenerative bone disease predominantly in postmenopausal women. Green tea polyphenols (GTP) and Tai Chi (TC) have been shown to be beneficial on human bone health.
Guoqing Qian, Kathy Xue, Lili Tang, Franklin Wang, Xiao Song, Ming-Chien Chyu, Barbara C Pence, Chwan-Li Shen, Jia-Sheng Wang   +8 more
doaj   +1 more source

Game Transfer Phenomena in video game playing: a qualitative interview study [PDF]

, 2011
Video game playing is a popular activity and its enjoyment among frequent players has been associated with absorption and immersion experiences. This paper examines how immersion in the video game environment can influence the player during the game and ...
Aronsson, K, Griffiths, MD, Ortiz de Gortari, AB   +2 more
core  

Identifying conformational changes with site-directed spin labeling reveals that the GTPase domain of HydF is a molecular switch [PDF]

, 2017
[FeFe]-hydrogenases catalyse the reduction of protons to hydrogen at a complex 2Fe[4Fe4S] center called H-cluster. The assembly of this active site is a multistep process involving three proteins, HydE, HydF and HydG.
Acquasaliente, Laura, Bortolus, Marco, Carbonera, Donatella, Costantini, Paola, DE FILIPPIS, Vincenzo, DE ROSA, Edith, Doni, Davide, Galazzo, Laura, Maso, Lorenzo   +8 more
core   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source