Results 111 to 120 of about 153,070 (268)
FEBS Letters, 1995 Tissue transglutaminase (tTgase) is a GTP‐binding Ca2+‐dependent enzyme which catalyses the post‐translational modification of proteins via ϵ(γ‐glutamyl) lysine bridges. Recent evidence suggests that the GTP‐binding activity of tTgase may be important in intracellular signalling thus explaining some of the diverse suggested roles for the enzyme. In the
MIAN S +5 more
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The GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunits
International Journal of Biological Sciences, 2005 The heterotrimeric G-protein alpha subunit has long been considered a bimodal, GTP-hydrolyzing switch controlling the duration of signal transduction by seven-transmembrane domain (7TM) cell-surface receptors.
doaj
The GTP binding proteins Gem and Rad are negative regulators of the Rho–Rho kinase pathway [PDF]
, 2002 Yvona Ward +6 more
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The architecture of the Rag GTPase signaling network [PDF]
, 2017 The evolutionarily conserved target of rapamycin complex 1 (TORC1) couples an array of intra- and extracellular stimuli to cell growth, proliferation and metabolism, and its deregulation is associated with various human pathologies such as ...
De Virgilio, Claudio +3 more
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FEBS LettersκB‐Ras (NF‐κB inhibitor‐interacting Ras‐like protein) GTPases are small Ras‐like GTPases but harbor interesting differences in important sequence motifs.
René Rasche +4 more
semanticscholar +1 more source
Correction: Oncogene ect2 is related to regulators of small GTP-binding proteins [PDF]
, 1993 Toru Miki +4 more
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Regulation of phospholipase C-delta by GTP-binding proteins-rhoA as an inhibitory modulator
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1998 The regulation of Phospholipase C (PLC)delta activity remains obscure. These studies show that PLCdelta1 activity is significantly enhanced by both guanosine thiotriphosphate (GTPgammaS) and Clostridium botulinum exoenzyme C3 (C3) but not by aluminium fluoride.
Hodson, Elizabeth A.M +3 more
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Phosphatidylserine polarization is required for proper Cdc42 localization and for development of cell polarity. [PDF]
, 2010 We used genetically-encoded fluorescent probes to visualize the distribution of phosphatidylserine (PS) in live S. cerevisiae. The majority of the PS was found to reside in the cytosolic leaflet of the plasma membrane.
Gregory Fairn, Sergio Grinstein
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D₂ Dopamine Receptors Colocalize Regulator of G-Protein Signaling 9-2 (RGS9-2) via the RGS9 DEP Domain, and RGS9 Knock-Out Mice Develop Dyskinesias Associated with Dopamine Pathways [PDF]
, 2005 Regulator of G-protein signaling 9-2 (RGS9-2), a member of the RGS family of Gα GTPase accelerating proteins, is expressed specifically in the striatum, which participates in antipsychotic-induced tardive dyskinesia and in levodopa-induced dyskinesia. We
Axelrod, Jeffrey D. +10 more
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