Targeted Quantitative Profiling of GTP-Binding Proteins Associated with Metastasis of Melanoma Cells. [PDF]
J Proteome Res, 2021 Cai R +5 more
europepmc +1 more source
GAP activity, but not subcellular targeting, is required for Arabidopsis RanGAP cellular and developmental functions [PDF]
, 2015 The Ran GTPase activating protein (RanGAP) is important to Ran signaling involved in nucleocytoplasmic transport, spindle organization, and postmitotic nuclear assembly.
Boruc, Joanna +6 more
core +2 more sources
Deciphering the Impact of RAC1‐SPTAN1 in ARPKD Cystogenesis Using Multifaceted Models
Advanced Science, EarlyView.Distal/connecting tubules expressing SLC8A1 have been suggested as a potential origin of ARPKD cysts. SPTAN1 has been identified as a key molecule in ARPKD cyst formation. Restoring SPTAN1 in PKHD1−/− organoids reduced cyst formation, normalized calcium levels, and decreased RAC1/c‐FOS expression, highlighting SPTAN1's role in ARPKD and the potential ...
Shohei Kuraoka +9 more
wiley +1 more source
Phylogenetic and Expression Studies of Small GTP-Binding Proteins in Solanum lycopersicum Super Strain B. [PDF]
Plants (Basel), 2022 Al-Zahrani HS +4 more
europepmc +1 more source
A Rab10:RalA G protein cascade regulates insulin-stimulated glucose uptake in adipocytes. [PDF]
, 2014 Insulin-stimulated glucose uptake in fat and muscle is mediated by the major facilitative glucose transporter Glut4. Insulin controls the trafficking of Glut4 to the plasma membrane via regulation of a series of small G proteins, including RalA and Rab10.
Chen, Xiao-Wei +6 more
core +1 more source
Ferroptosis: The Demise of Cells Through Phospholipid Peroxidation
Advanced Science, EarlyView.The relative abundance of peroxidation‐resistant monounsaturated fatty acids (MUFAs) vs. peroxidation‐sensitive polyunsaturated fatty acids (PUFAs) incorporated into phospholipid (PL) is a key determinant of ferroptosis sensitivity, as the peroxidation of PL PUFA acyl chains (PUFA‐PL) disrupts membrane integrity, causing ferroptotic cell death ...
Shaojie Cui, Jin Ye
wiley +1 more source
ADP-Ribosylation Factor Family of Small GTP-Binding Proteins: Their Membrane Recruitment, Activation, Crosstalk and Functions. [PDF]
Front Cell Dev Biol, 2022 Li T, Guo Y.
europepmc +1 more source
Post‐Translational Regulation of CD8+ T Cell Fate and Dysfunction in Tumor Immunity
Advanced Science, EarlyView.This review delineates how post‐translational modifications (PTMs) function as a central regulatory interface governing CD8+ T cell activation, differentiation, persistence, and exhaustion in antitumor immunity. By integrating antigenic, metabolic, and microenvironmental cues, diverse PTM programs coordinate transcriptional and chromatin states that ...
Zihao Zhou +8 more
wiley +1 more source
GLOBAL AND TARGETED PROFILING OF GTP-BINDING PROTEINS IN BIOLOGICAL SAMPLES BY MASS SPECTROMETRY. [PDF]
Mass Spectrom Rev, 2021 Huang M, Wang Y.
europepmc +1 more source
Study of the Effect of Gedunin against Protein-GTP-Binding Protein RAD to Treat Diabetes: An In-Silico Approach [PDF]
, 2021 Varsha Prajapati +2 more
openalex