Results 161 to 170 of about 236,650 (321)

A Process Model of Rho GTP-binding Proteins in the Context of Phagocytosis

, 2008
Luca Cardelli, Philippa Gardner, Ozan Kahramanoğulları   +2 more
openalex   +1 more source

Activity of 1,3-β-D-Glucan Synthase Requires the GTP-binding Protein Rho1 [PDF]

, 1996
Paul Mazur, Walter F. Baginsky
openalex   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

Medicinal Research Reviews, EarlyView.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova, Hana Navratilova, Kamil Musilek, Ondrej Benek   +3 more
wiley   +1 more source

Transmission of cellular information through GTP-binding protein.

, 1988
Kimihiko Kameyama, Michio Ui
openalex   +2 more sources

Recent Progress in Treating Airway Mucus Hypersecretion by Targeting the Epidermal Growth Factor Receptor Signaling Pathway

Pediatric Discovery, EarlyView.
ABSTRACT Asthma, chronic pulmonary obstructive disease (COPD), cystic fibrosis, and acute respiratory infections are severe respiratory conditions that significantly contribute to global morbidity and mortality. Airway mucus hypersecretion is an important common pathophysiological and clinical manifestation of these diseases and is closely associated ...
Yuanyuan Zhang, Fuping Yang, Chunyu Yan, Yu Deng, Enmei Liu   +4 more
wiley   +1 more source

QSP Modeling Shows Pathological Synergism Between Insulin Resistance and Amyloid‐Beta Exposure in Upregulating VCAM1 Expression at the BBB Endothelium

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 561-571, March 2025.
ABSTRACT Type 2 diabetes mellitus (T2DM), characterized by insulin resistance, is closely associated with Alzheimer's disease (AD). Cerebrovascular dysfunction is manifested in both T2DM and AD, and is often considered as a pathological link between the two diseases.
Zengtao Wang, Vaishnavi Veerareddy, Xiaojiao Tang, Kevin J. Thompson, Sunil Krishnan, Krishna R. Kalari, Karunya K. Kandimalla   +6 more
wiley   +1 more source

Mutations in Exon 7 of the GTP-Binding Protein Gs.ALPHA. Were Not a Common Cause of Pseudohypoparathyroidism with Albright's Hereditary Osteodystrophy in Japanese.

, 1997
Kyoko Takeda, Minao YOKOYAMA, Kozo Hashimoto, Yuji Hiromatsu, Hidekata Yamanaka, TAEKO SHIMIZU, Masahide Sasaki   +6 more
openalex   +2 more sources

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

Small, EarlyView.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti, Marius F.W. Trollmann, Christina Wichmann, Thomas Gutsmann, Christian Eggeling, Rainer A. Böckmann   +5 more
wiley   +1 more source

5′-triphosphate guanosine RNAs recruit GTP-binding proteins to suppress RIG-I/IFN type I signaling

, 2023
Szymanski J, Wolczyk M, Trus I, Naz Z, Idlin N, Jackiewicz J, Nowak E, Wuebben C, Hartmann G, Rappsilber J, Michlewski G.   +10 more
europepmc   +1 more source

Nucleotide exchange-dependent and nucleotide exchange-independent functions of plant heterotrimeric GTP-binding proteins. [PDF]

Sci Signal, 2019
Maruta N, Trusov Y, Chakravorty D, Urano D, Assmann SM, Botella JR.   +5 more
europepmc   +1 more source