Results 291 to 300 of about 232,963 (342)

The Influence of Schwann Cell Metabolism and Dysfunction on Axon Maintenance

Glia, Volume 73, Issue 12, Page 2338-2352, December 2025.
Main Points Sensory neurons depend on Schwann cells for survival. Schwann cells provide energy for axons dunng rapid firing or after injury. Dysregulated metabolism in Schwann cells can lead to the production of neurotoxic and axon degeneration. ABSTRACT Schwann cells are the glial cells in the peripheral nervous system responsible for the production ...
Rose Follis, Vishwanath V. Prabhu, Bruce D. Carter   +2 more
wiley   +1 more source

A FtsZ inhibitor-acinetobactin conjugate with enhanced cellular uptake in Acinetobacter baumannii acts synergistically in combination with PBP3-targeting antibiotics. [PDF]

PLoS One
Bryan EJ, Szekely Z, Wang Y, Fan H, Moynié L, Roberge JY, Pilch DS.   +6 more
europepmc   +1 more source

The crystal structure of Thermus thermophilus UMP kinase complexed with a phosphoryl group acceptor and donor. [PDF]

PLoS One
Fukui K, Nishiwaki A, Nakagawa N, Kuramitsu S, Masui R.   +4 more
europepmc   +1 more source

Structural mechanisms for cold‐adapted activity of phosphoenolpyruvate carboxykinase

Protein Science, Volume 34, Issue 11, November 2025.
Abstract Temperature is a critical factor in enzyme function, as most enzymes are thermally activated. Across Earth's diverse environments (−20 to 120°C), enzymes have evolved to function optimally at their organism's growth temperature. Thermophilic enzymes must resist denaturation, while psychrophilic enzymes must maintain activity with limited ...
Matthew J. McLeod, Shauhin Yazdani, Sarah A. E. Barwell, Todd Holyoak   +3 more
wiley   +1 more source

A Rac-specific competitive inhibitor of guanine nucleotide binding reduces metastasis in triple-negative breast cancer. [PDF]

Cell Rep Med
Dilasser F, Rose L, Quemener A, Ferrandez Y, Hassoun D, Rousselle M, Bergereau H, Lambot SM, Anselmino LE, Trouillet C, Andre G, Maillasson M, Croyal M, Riviere M, Dubreuil D, Collet S, Souaze F, Campone M, Patsouris A, Mortier E, Marquez MM, Juin P, Lebreton J, Tessier A, Cherfils J, Loirand G, Sauzeau V.   +26 more
europepmc   +1 more source

Functional Analysis of Rare RAS Variants of Unknown Significance. [PDF]

Cancer Res Commun
Park S, Ikegami M, Kitada R, Takamochi K, Suzuki K, Mano H, Kohsaka S.   +6 more
europepmc   +1 more source

Methods for Controlling Small GTPase Activity. [PDF]

Chembiochem
Faulkner B, He Y, Sitrin D, Stains CI.
europepmc   +1 more source

Structural basis of pseudoGTPase-mediated protein-protein interactions. [PDF]

Structure
Wang B, Yang R, Wan C, Tian Y, Wu J, Adewole TS, Roy S, Li S, Shen J, Yin Q.   +9 more
europepmc   +1 more source

A tubulin-binding protein that preferentially binds to GDP-tubulin and promotes GTP exchange. [PDF]

J Biol Chem
Yon WJ, Ha T, Zheng Y, Pedersen RTA.
europepmc   +1 more source

Wheat Small GTPase Gene TaRABH1bL Is Involved in High-Temperature All-Stage Resistance to Puccinia striiformis f. sp. tritici. [PDF]

Mol Plant Pathol
Shi Y, Bao X, Li H, Li Y, Chen X, Hu X.
europepmc   +1 more source