Results 301 to 310 of about 1,111,922 (385)

Functional interactions of stimulatory and inhibitory GDP/GTP exchange proteins and their common substrate small GTP-binding protein.

, 1992
Akira Kikuchi, Shinya Kuroda, Takuya Sasaki, K. Kotani, Kouji Hirata, Masahiko Katayama, Yoshimi Takai   +6 more
openalex   +1 more source

Effect of Tirzepatide Treatment on Hepatic Biomarkers in Patients With Metabolic Dysfunction‐Associated Steatotic Liver Disease and Type 2 Diabetes Mellitus

Hepatology Research, EarlyView.
This study evaluated the effects of tirzepatide in patients with Type 2 diabetes mellitus and metabolic dysfunction‐associated steatotic liver disease. After 48 weeks of treatment, patients showed significant improvements in liver steatosis and injury, surrogate markers of liver fibrosis, glycemic control, and body weight. ABSTRACT Aim This study aimed
Taeang Arai, Masanori Atsukawa, Chikako Nagao, Zento Yamada, Takahiro Rokugo, Kenta Suzuki, Michika Kitamura, Tetsuyuki Higashi, Kaori Koyano, Yuta Hasegawa, Tadamichi Kawano, Hiroki Ono, Yuji Yoshida, Tomomi Okubo, Korenobu Hayama, Ai Nakagawa‐Iwashita, Norio Itokawa, Chisa Kondo, Mototsugu Nagao, Masato Iwabu, Katsuhiko Iwakiri   +20 more
wiley   +1 more source

Drp1 Proteins Released from Hydrolysis-Driven Scaffold Disassembly Trigger Nucleotide-Dependent Membrane Remodeling to Promote Scission. [PDF]

J Am Chem Soc
Luo EW, Nolden KA, Alimohamadi H, Lee MW, Duan L, Hill RB, Wong GCL.   +6 more
europepmc   +1 more source

Biochemical characterization of phosphoenolpyruvate carboxykinases from multiple species of brown algae

Journal of Phycology, EarlyView.
Abstract Phosphoenolpyruvate carboxykinase (PEPCK) is involved in the conversion of phosphoenolpyruvate (PEP) to oxaloacetate (OAA). In addition to playing a role in gluconeogenesis in various organisms, PEPCK also functions in the C4 cycle to concentrate CO2 for photosynthesis in some C4 plants.
Jian‐qiang Jin, Yuusuke Yokooji, Toshiyuki Shibata, Haruyuki Atomi   +3 more
wiley   +1 more source

The evolution of RHO of plant (ROP) proteins and their morphogenetic functions

New Phytologist, EarlyView.
Summary The ability of a cell to polarise, and direct cell growth or orient cell division, for example, is fundamental for the morphogenesis of multicellular organisms. A key molecular system for signalling cell polarity in diverse eukaryotes involves the RHO family of small GTPases.
Hugh Mulvey, Liam Dolan
wiley   +1 more source

GoLoco/GPR motif-dependent regulation of Rap1GAP1 by Gα_o is disrupted by Gα_o encephalopathy variants. [PDF]

J Biol Chem
Momplaisir NL, Chandan NR, Wang B, Qu E, Smrcka AV.   +4 more
europepmc   +1 more source

Guanylate‐binding proteins: emerging critical functions in plant development, immunity and stress response

New Phytologist, EarlyView.
Summary Guanylate‐binding proteins (GBPs) are large GTPases that belong to the Dynamin Superfamily Protein family. In humans, GBPs are well‐characterized interferon‐induced GTPases, playing a central role in cell‐autonomous innate immunity against infections, inflammation and cancer. GBPs orthologs have been identified in plants only recently.
Lucie Fernandez‐Lochu, Martine Lemaire‐Chamley, Christian Chevalier   +2 more
wiley   +1 more source

Evolution of structure-guided drug design strategies targeting mutations in codon 12 of KRAS. [PDF]

RSC Med Chem
Dorandish S, Bhayekar K, Singh A, Kushwaha ND, Malin E, Serafimovski S, Kelm JM, Gavande NS, Lakkaniga NR.   +8 more
europepmc   +1 more source

Tolerance to Phosphorus Deficiency Improves Seed Phytic Acid‐to‐Iron Molar Ratios in Common Bean

Plant, Cell &Environment, EarlyView.
ABSTRACT Although significant advances have been achieved in the biofortification of common beans to overcome deficiencies in Zinc (Zn) and iron (Fe), the mechanisms involved remain poorly understood. We thus explored the relationships between phosphorus nutrition and Zn and Fe accumulation in four bean genotypes (Edar, Nizok, Colorado and Chimbolos ...
Barbara Karpinska, Christine H. Foyer
wiley   +1 more source

The ubiquitin code of RAS proteins: Decoding its role in cancer progression. [PDF]

iScience
Shi Y, Shen Y, Zhang X, Zhu N, Ding Y, Yuan Y, Wang J.   +6 more
europepmc   +1 more source