Results 341 to 350 of about 1,111,922 (385)
Some of the next articles are maybe not open access.
Purification of a GTP-Binding Protein Localized in Mitochondria1
The Journal of Biochemistry, 1993A particulate fraction consisting of heavy organelles such as nuclei and mitochondria was prepared from Ehrlich ascites tumor cells. From this fraction we have purified a GTP-binding protein with a molecular mass of 33 kDa (MTG33) by guanidine hydrochloride extraction followed by four steps of column chromatography. The Kd value of MTG33 for GTP was 17
Shizu Takeda +4 more
openaire +3 more sources
GTP-binding proteins in intracellular transport
Trends in Cell Biology, 1992One of the most exciting recent discoveries in the area of intracellular protein transport is the finding that many organelles involved in exocytic and endocytic membrane traffic have one or more Ras-like GTP-binding proteins on their cytoplasmic face that are specific for each membranous compartment.
openaire +3 more sources
Small GTP-binding proteins in Plasmodium falciparum
Biology of the Cell, 1996Summary— During its erythrocytic life cycle Plasmodium falciparum exchanges compounds with host cells through phagocytosis and exocytosis. In eucaryotic cells, small GTP‐binding proteins of the Ras superfamily appear to be involved in different steps of membrane trafficking and in intracellular signals.
Birgitta Olofsson +4 more
openaire +3 more sources
GTP-binding Proteins and Signal Transduction
2002Being metabolic regulators, nucleotides play many other roles rather than just providing the alphabets of the genetic code. The pyrimidine bases act as identifiers for metabolites. Purine nucleotides play their main regulatory roles in association with proteins, not metabolites.
Peter E.R. Tatham +2 more
openaire +2 more sources
The Role of GTP-Binding Proteins in Platelet Activation
Thrombosis and Haemostasis, 1991SummaryPlatelet activation begins with the binding of an agonist to the cell surface and culminates in the events of platelet aggregation, secretion and clot formation. Recent studies have identified two large families of GTP-binding proteins in platelets that are thought to participate in the events of platelet activation. The first of these are the G
David R. Manning, Lawrence F. Brass
openaire +3 more sources
Identification and isoprenylation of plant GTP-binding proteins
Plant Molecular Biology, 1996To identify isoprenylated plant GTP-binding proteins, Arabidopsis thaliana and Nicotiana tabacum cDNA expression libraries were screened for cDNA-encoded proteins capable of binding [32P]GTP in vitro. ATGB2, an Arabidopsis homologue of the GTP-binding protein Rab2, was found to bind GTP in vitro and to be a substrate for a geranylgeranyl:protein ...
Stephen K. Randall +2 more
openaire +3 more sources
GTP Binding Proteins in Platelets
1999Cells are constantly engulfed in an environment of electrical and chemical stimuli. Specific receptors enable cells to differentiate among the stimuli and relay a specific message that leads to a defined cellular response. The process that translates the stimulus-receptor interaction into an intracellular chemical message is termed signal transduction.
openaire +2 more sources
GTP-binding proteins and early embryogenesis in Xenopus
Cellular Signalling, 1995During early embryogenesis the specification of body axes and the determination of cell subtypes proceeds through cell interactions and movements which involve the decoding of various signals in a spatial and temporal manner. An increasingly abundant literature has revealed the participation of growth factors and their receptors in the induction and ...
Laurent Paquereau, Yves Audigier
openaire +3 more sources
GE: A GTP-Binding Protein Mediating Exocytosis
Annual Review of Physiology, 1990Recent advances in the field of exocytotic secretion have depended almost exclusively on the use of permeabilized cells that allow the composition of the cytosol to be precisely controlled. Many agents and strategies for plasma membrane permeabilization have been utilized (see Table 1), and it is impor tant to appreciate that these generate, in the ...
openaire +3 more sources
Activation of Small GTP-Binding Proteins
1999Guanosine triphosphate- (GTP-) binding proteins act as molecular switches: active in GTP-bound form and inactivated when bound GTP is hydrolyzed. Switching on these proteins initiates a wide range of cellular responses and is controlled by multiple factors.
Anna Koffer, Richard Sullivan
openaire +2 more sources