Results 141 to 150 of about 5,611 (205)

From a clinically relevant pain target to a possible analgesic treatment strategy

Neurotherapeutics
Alban Latremoliere
doaj   +1 more source

Validating the GTP-cyclohydrolase 1-feedback regulatory complex as a therapeutic target using biophysical and in vivo approaches. [PDF]

Br J Pharmacol, 2015
Hussein D, Starr A, Heikal L, McNeill E, Channon KM, Brown PR, Sutton BJ, McDonnell JM, Nandi M.   +8 more
europepmc   +1 more source

Erythropoietin prevents endothelial dysfunction in GTP-cyclohydrolase I-deficient hph1 mice. [PDF]

J Cardiovasc Pharmacol, 2014
dʼUscio LV, Santhanam AV, Katusic ZS.
europepmc   +1 more source

Characterization of cerebral microvasculature in transgenic mice with endothelium targeted over-expression of GTP-cyclohydrolase I. [PDF]

Brain Res, 2015
Santhanam AV, d'Uscio LV, Katusic ZS.
europepmc   +1 more source

Asymmetrical leg atrophy in levodopa-responsive dystonia due to a novel GTP cyclohydrolase mutation. [PDF]

Mov Disord, 2014
Mulroy E, McCarthy A, Lynch T, Costello D, Ross OA.   +4 more
europepmc   +1 more source

Riboflavin Biosynthesis: Mapping the Tagged Lines of a Complex Metabolic Design. [PDF]

Biochemistry
Hoffpauir ZA, Lamb AL.
europepmc   +1 more source

Cell-autonomous role of endothelial GTP cyclohydrolase 1 and tetrahydrobiopterin in blood pressure regulation. [PDF]

Hypertension, 2014
Chuaiphichai S, McNeill E, Douglas G, Crabtree MJ, Bendall JK, Hale AB, Alp NJ, Channon KM.   +7 more
europepmc   +1 more source

Overexpression of GTP cyclohydrolase 1 feedback regulatory protein is protective in a murine model of septic shock. [PDF]

Shock, 2014
Starr A, Sand CA, Heikal L, Kelly PD, Spina D, Crabtree M, Channon KM, Leiper JM, Nandi M.   +8 more
europepmc   +1 more source

Paracrine effect of GTP cyclohydrolase and angiopoietin-1 interaction in stromal fibroblasts on tumor Tie2 activation and breast cancer growth. [PDF]

Oncotarget, 2016
Chen L, Zeng X, Kleibeuker E, Buffa F, Barberis A, Leek RD, Roxanis I, Zhang W, Worth A, Beech JS, Harris AL, Cai S.   +11 more
europepmc   +1 more source