Results 181 to 190 of about 137,270 (354)

Versatile DNA Hydrogel‐Mediated Delivery of Ginsenoside‐Encapsulated Small Extracellular Vesicles to Boost Diabetic Wound Repair

Advanced Science, EarlyView.
This study presents a DNA hydrogel‐mediated delivery system, in which ginsenoside (GS) molecules are incorporated into small extracellular vesicles (sEV) secreted by mesenchymal stem cells (MSCs) and the formed complexes are then anchored in DNA hydrogels via aptamer‐CD63 affinity as “GS/sEV@DNAgels”, to improve diabetic wound repair.
Jianming Xing, Shuangyang Li, Yuning Wang, Xushuang Jia, Ruiting Lin, Xintong Liu, Dongxu Wang, Ning Cui, Peng Ji, Jiaqi Chen, Shengnian Wang, Guangzhe Li, Ye Teng, Da Liu, Ye Jin   +14 more
wiley   +1 more source

Ral GTPase-activating protein regulates the malignancy of pancreatic ductal adenocarcinoma. [PDF]

Cancer Sci, 2021
Yoshimachi S, Shirakawa R, Cao M, Trinh DA, Gao P, Sakata N, Miyazaki K, Goto K, Miura T, Ariake K, Maeda S, Masuda K, Ishida M, Ohtsuka H, Unno M, Horiuchi H.   +15 more
europepmc   +1 more source

CRL4A-FBXW5-mediated degradation of DLC1 Rho GTPase-activating protein tumor suppressor promotes non-small cell lung cancer cell growth

, 2020
T. Y. Kim, S. Jackson, Y. Xiong, T. G. Whitsett, J. R. Lobello, G. J. Weiss, N. L. Tran, Y.-J. Bang, C. J. Der   +8 more
openalex   +1 more source

Insulin Receptor-mediated p62dok Tyrosine Phosphorylation at Residues 362 and 398 Plays Distinct Roles for Binding GTPase-activating Protein and Nck and Is Essential for Inhibiting Insulin-stimulated Activation of Ras and Akt [PDF]

, 2001
Michael J. Wick, Lily Dong, Derong Hu, Paul R. Langlais, Feng Liu   +4 more
openalex   +1 more source

A Solution for Exosome‐Based Analysis: Surface‐Enhanced Raman Spectroscopy and Artificial Intelligence

Advanced Intelligent Discovery, EarlyView.
Exosomes are emerging as powerful biomarkers for disease diagnosis and monitoring. This review highlights the integration of surface‐enhanced Raman spectroscopy with artificial intelligence to enhance molecular fingerprinting of exosomes. Machine learning and deep learning techniques improve spectral interpretation, enabling accurate classification of ...
Munevver Akdeniz, Zakarya Al‐Shaebi, Omer Aydin   +2 more
wiley   +1 more source

Solution structure and dynamics of the mitochondrial-targeted GTPase-activating protein (GAP) VopE by an integrated NMR/SAXS approach. [PDF]

Protein Sci, 2022
Smith KP, Lee W, Tonelli M, Lee Y, Light SH, Cornilescu G, Chakravarthy S.   +6 more
europepmc   +1 more source

Rho GTPase-activating protein 17 (ARHGAP17) as additional autoimmune target in ARHGAP26-IgG/anti-Ca autoantibody-associated autoimmune encephalitis. [PDF]

J Neurol, 2023
Jarius S, Haas J, Wildemann B.
europepmc   +1 more source

IQ Motif-Containing GTPase-Activating Protein 2 (IQGAP2) Is a Novel Regulator of Colonic Inflammation in Mice

, 2015
Amr M. Ghaleb, Agnieszka B. Bialkowska, Ashley J. Snider, Dmitri V. Gnatenko, Yusuf A. Hannun, Vincent W. Yang, Valentina A. Schmidt   +6 more
openalex   +2 more sources

Infantile‐Onset Ascending Hereditary Spastic Paraplegia due to a Homozygous ALS2 Exons 24–25 Deletion: Expanding the Genotypic Spectrum

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT We describe a novel homozygous intragenic deletion in the ALS2 gene in an 8‐year‐old boy with Infantile‐onset Ascending Hereditary Spastic Paraplegia (IAHSP) and oculomotor apraxia, thereby contributing to the expanding genetic landscape of ALS2‐related disorders.
Vito Luigi Colona, Maria Gnazzo, Silvia Genovese, Gessica Vasco, Lorena Travaglini, Maurizio Sabbadini, Marina Macchiaiolo, Francesco Nicita, Jacopo Sartorelli, Carmelo Piscopo, Enrico Castelli, Enrico Bertini, Andrea Bartuli, Antonio Novelli, Gessica Della Bella, Davide Vecchio   +15 more
wiley   +1 more source

Saccharomyces cerevisiae Gcs1 is an ADP-ribosylation factor GTPase-activating protein.

, 1996
Pak P. Poon, Xuejun Wang, Miriam Rotman, Irit Huber, Edna Cukierman, Dan Cassel, Richard A. Singer, Gerald C. Johnston   +7 more
openalex   +2 more sources