Transient Cerebral Ischemia Increases Tyrosine Phosphorylation of the Synaptic RAS-GTPase Activating Protein, SynGAP [PDF]
Lin Pei+3 more
openalex +1 more source
The transcription factor RIP140 regulates interferon γ signaling in breast cancer
What's New? Interferon γ (IFNγ) is a key player in breast cancer, with the potential to induce apoptosis and to shift tumors into a dormant state. However, it also may promote carcinogenesis and angiogenesis. In this study, transcriptomic analysis identified the transcription factor RIP140 as a key regulator of IFNγ signaling in breast cancer.
Stéphan Jalaguier+9 more
wiley +1 more source
Modulation of RASD2 by miRNA‐485‐5p Drives Thyroid Cancer Progression and Metastasis
ABSTRACT This study investigates the role of RASD2 (Ras Homolog Enriched In Striatum) in thyroid carcinoma progression and its modulation by microRNA‐485‐5p. Differential RASD2 expression patterns were initially identified through bioinformatic analysis of public databases.
Xiao‐Yu Li+7 more
wiley +1 more source
The Rac GTPase-activating Protein RotundRacGAP Interferes with Drac1 and Dcdc42 Signalling in Drosophila melanogaster [PDF]
Karine Raymond+5 more
openalex +1 more source
Abstract Affinity photolabeling is a smart method to study noncovalent and transient interactions and provide a submolecular picture of the contacts between interacting partners. In this review, we will focus on the identification of peptide partners using photoaffinity labeling coupled to mass spectrometry in different contexts such as in vitro with a
Astrid Walrant, Emmanuelle Sachon
wiley +1 more source
The Arf GTPase-activating protein ASAP1 regulates the actin cytoskeleton
Paul A. Randazzo+7 more
openalex +1 more source
The Association of ASAP1, an ADP Ribosylation Factor-GTPase Activating Protein, with Focal Adhesion Kinase Contributes to the Process of Focal Adhesion Assembly [PDF]
Yunhao Liu+4 more
openalex +1 more source
Recent Developments in the Optical Control of Adrenergic Signaling
ABSTRACT Adrenoceptors (ARs) play a vital role in various physiological processes and are key therapeutic targets. The advent of optical control techniques, including optogenetics and photopharmacology, offers the potential to modulate AR signaling with precise temporal and spatial resolution. In this review, we summarize the latest advancements in the
Shuang Shi+4 more
wiley +1 more source
In Vivo Rho GTPase-Activating Protein Activity of Pseudomonas aeruginosa Cytotoxin ExoS [PDF]
Rebecca Krall+3 more
openalex +1 more source