Key Regulators of Parasite Biology Viewed Through a Post‐Translational Modification Repertoire
ABSTRACT Parasites are the leading causes of morbidity and mortality in both humans and animals, imposing substantial socioeconomic burdens worldwide. Controlling parasitic diseases has become one of the key issues in achieving “One Health”. Most parasites have sophisticated life cycles exhibiting progressive developmental stages, morphologies, and ...
Naiwen Zhang, Ning Jiang, Qijun Chen
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Phosphoinositide-dependent Activation of the ADP-ribosylation Factor GTPase-activating Protein ASAP1
Jeanelle L. Kam+8 more
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Comparative Proteomics of Salinity Stress Responses in Fish and Aquatic Invertebrates
ABSTRACT Fluctuating salinity is symptomatic of climate change challenging aquatic species. The melting of polar ice, rising sea levels, coastal surface and groundwater salinization, and increased evaporation in arid habitats alter salinity worldwide. Moreover, the frequency and intensity of extreme weather events such as rainstorms and floods increase,
Maxime Leprêtre+3 more
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Pseudomonas aeruginosa ExoT Acts In Vivo as a GTPase-Activating Protein for RhoA, Rac1, and Cdc42 [PDF]
Barbara I. Kazmierczak, Joanne N. Engel
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Glycoproteomics and Its Role in Understanding Bacterial O‐Linked Glycosylation
ABSTRACT Protein glycosylation is now recognized as a ubiquitous process observed in all domains of life. Within bacterial species, carbohydrates can be attached to multiple residues with glycosylation of serine, threonine, or tyrosine residues via their hydroxyl side chains referred to as O‐linked glycosylation.
Kristian I. Karlic+2 more
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Rabconnectin-3, a Novel Protein That Binds Both GDP/GTP Exchange Protein and GTPase-activating Protein for Rab3 Small G Protein Family [PDF]
Fumiko Nagano+7 more
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Proteomic Insight Into Alzheimer's Disease Pathogenesis Pathways
ABSTRACT Alzheimer's disease (AD) is a leading cause of dementia, but the pathogenesis mechanism is still elusive. Advances in proteomics have uncovered key molecular mechanisms underlying AD, revealing a complex network of dysregulated pathways, including amyloid metabolism, tau pathology, apolipoprotein E (APOE), protein degradation ...
Taekyung Ryu+3 more
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Pseudomonas aeruginosa ExoT Is a Rho GTPase-Activating Protein
Rebecca Krall+3 more
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Endocytosis of Epidermal Growth Factor Receptor Regulated by Grb2-mediated Recruitment of the Rab5 GTPase-activating Protein RN-tre [PDF]
Lenka Martinu+3 more
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RNAi technology development for weed control: all smoke and no fire?
Despite the potential of Spray‐Induced Gene Silencing in weed management several critical points such as molecular target, weed species of interest as well as delivery techniques need to be addressed. Abstract RNA interference (RNAi) technology, specifically Spray‐Induced Gene Silencing (SIGS), holds potential as an innovative approach for selective ...
Silvia Panozzo+4 more
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