Role of Coatomer and Phospholipids in GTPase-activating Protein-dependent Hydrolysis of GTP by ADP-ribosylation Factor-1 [PDF]
Edith Szafer+5 more
openalex +1 more source
Phosphorylation at the Helm: Kinase‐Mediated Regulation of Primary Cilia Assembly and Disassembly
ABSTRACT The primary cilium serves as an antenna of most vertebrate cells and is important for conveying cues from several signaling pathways into appropriate cellular responses during development and homeostasis. Cilia assembly and disassembly processes are thought to be strictly controlled; however, the precise nature of molecular events underlying ...
Andrea Lacigová, Lukáš Čajánek
wiley +1 more source
Aberrant expression of GTPase-activating protein ARAP1 triggers circular dorsal ruffles associated with malignancy in hepatocellular carcinoma Hep3B cells. [PDF]
Sun X+12 more
europepmc +1 more source
Interaction Between Actin and Microtubules During Plant Development
ABSTRACT The dynamic interaction between actin filaments (AFs) and microtubules (MTs) plays a crucial role in regulating key developmental and physiological processes in plant cells, particularly in the formation of specialized cell types with distinct shapes and functions, such as pollen tubes, trichomes, and leaf epidermal cells.
Zining Wu+3 more
wiley +1 more source
Clinical significance of upregulated Rho GTPase activating protein 12 causing resistance to tyrosine kinase inhibitors in hepatocellular carcinoma. [PDF]
Wang XW+13 more
europepmc +1 more source
Biochemical characterization of the GTPase-activating protein GAP1\(^{IP4BP}\)
Als Mitglied der GAP1 Familie der Ras GTPase aktivierenden Proteinen (RasGAPs) besitzt GAP1\(^{IP4BP}\) eine hohe Sequenzhomologie zu anderen RasGAPs, es zeigt jedoch keinerlei Sequenzhomologie zu allen bekannten RapGAPs. Neben der vorhergesagten RasGAP-Aktivität zeigt GAP1\(^{IP4BP}\) jedoch auch eine unerwartete GAP-Aktivität für das Ras-verwandte ...
openaire +2 more sources
ABSTRACT Of the three types of cytoskeleton known in animals—actin, microtubules, and intermediate filaments—only actin and microtubules exist in plants. Both play important roles in cellular shaping, organelle movement, organization of the endomembrane system, and cell signaling.
Norman R. Groves+3 more
wiley +1 more source
The GTPase activating protein Gyp7 regulates Rab7/Ypt7 activity on late endosomes. [PDF]
Füllbrunn N+12 more
europepmc +1 more source
Rac GTPase activating protein 1 promotes gallbladder cancer via binding DNA ligase 3 to reduce apoptosis. [PDF]
Bian R+11 more
europepmc +1 more source