The carboxy-terminal catalytic domain of the GTPase-activating protein inhibits nuclear signal transduction and morphological transformation mediated by the CSF-1 receptor. [PDF]
Donna M. Bortner+3 more
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Specific TBC Domain-Containing Proteins Control the ER-Golgi-Plasma Membrane Trafficking of GPCRs
Summary: G-protein-coupled receptors (GPCRs) constitute the largest superfamily of cell surface signaling proteins. However, the molecular mechanisms underlying their cell surface delivery after synthesis remain poorly understood. Here, we screen the TBC
Zhe Wei+10 more
doaj
Cdc42 mobility and membrane flows regulate fission yeast cell shape and survival
Polarized exocytosis induced by local Cdc42 GTPase activity results in membrane flows that deplete low-mobility membrane-associated proteins. A reaction-diffusion particle model comprising Cdc42 positive feedback activation, hydrolysis by GTPase ...
David M. Rutkowski+3 more
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Interaction of two proline-rich sequences of cell adhesion kinase β with SH3 domains of p130Cas-related proteins and a GTPase-activating protein, Graf [PDF]
Takeaki Ohba+3 more
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Ran-binding Protein 1 (RanBP1) Forms a Ternary Complex with Ran and Karyopherin β and Reduces Ran GTPase-activating Protein (RanGAP) Inhibition by Karyopherin β [PDF]
Karen M. Lounsbury, Ian G. Macara
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Identification of a Sec4p GTPase-activating Protein (GAP) as a Novel Member of a Rab GAP Family [PDF]
Li‐Lin Du, Ruth Collins, Peter Novick
openalex +1 more source
Conserved charged residues in the leucine-rich repeat domain of the Ran GTPase activating protein are required for Ran binding and GTPase activation [PDF]
Jörg Haberland, Volker Gerke
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GAIP and RGS4 Are GTPase-Activating Proteins for the Gi Subfamily of G Protein α Subunits
D. M. Berman, T. Wilkie, A. Gilman
semanticscholar +1 more source