Results 151 to 160 of about 1,011,564 (289)

Specific TBC Domain-Containing Proteins Control the ER-Golgi-Plasma Membrane Trafficking of GPCRs

open access: yesCell Reports, 2019
Summary: G-protein-coupled receptors (GPCRs) constitute the largest superfamily of cell surface signaling proteins. However, the molecular mechanisms underlying their cell surface delivery after synthesis remain poorly understood. Here, we screen the TBC
Zhe Wei   +10 more
doaj  

Cdc42 mobility and membrane flows regulate fission yeast cell shape and survival

open access: yesNature Communications
Polarized exocytosis induced by local Cdc42 GTPase activity results in membrane flows that deplete low-mobility membrane-associated proteins. A reaction-diffusion particle model comprising Cdc42 positive feedback activation, hydrolysis by GTPase ...
David M. Rutkowski   +3 more
doaj   +1 more source

Signal Transduction in Neuronal Migration Roles of GTPase Activating Proteins and the Small GTPase Cdc42 in the Slit-Robo Pathway

open access: yesCell, 2001
Kit Wong   +12 more
semanticscholar   +1 more source

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