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Suppression of c-ras transformation by GTPase-activating protein

Nature, 1990
The ras genes are required for normal cell growth and mediate transformation by oncogenes encoding protein tyrosine kinases. Normal ras can transform cells in vitro and in vivo, but mutationally activated ras does so much more efficiently, and highly transforming mutant versions of ras have been isolated from a variety of human and animal tumours.
Alex G. Papageorge   +5 more
openaire   +3 more sources

An expanding role for RAS GTPase activating proteins (RAS GAPs) in cancer.

Advances in Biological Regulation, 2014
Ophélia Maertens, K. Cichowski
semanticscholar   +1 more source

GTPase-activating proteins: helping hands to complement an active site.

TIBS -Trends in Biochemical Sciences. Regular ed, 1998
K. Scheffzek   +2 more
semanticscholar   +1 more source

Nanooncology: The future of cancer diagnosis and therapy

Ca-A Cancer Journal for Clinicians, 2013
Avnesh S Thakor
exaly  

MicroRNAome genome: A treasure for cancer diagnosis and therapy

Ca-A Cancer Journal for Clinicians, 2014
Ioana Berindan-neagoe   +2 more
exaly  

Application of Nanotechnology in Cancer Therapy and Imaging

Ca-A Cancer Journal for Clinicians, 2008
Dong M Shin
exaly  

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