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Suppression of c-ras transformation by GTPase-activating protein
Nature, 1990The ras genes are required for normal cell growth and mediate transformation by oncogenes encoding protein tyrosine kinases. Normal ras can transform cells in vitro and in vivo, but mutationally activated ras does so much more efficiently, and highly transforming mutant versions of ras have been isolated from a variety of human and animal tumours.
Alex G. Papageorge+5 more
openaire +3 more sources
RGS family members: GTPase-activating proteins for heterotrimeric G-protein α-subunits
Nature, 1996N. Watson+4 more
semanticscholar +1 more source
An expanding role for RAS GTPase activating proteins (RAS GAPs) in cancer.
Advances in Biological Regulation, 2014Ophélia Maertens, K. Cichowski
semanticscholar +1 more source
GTPase-activating proteins: helping hands to complement an active site.
TIBS -Trends in Biochemical Sciences. Regular ed, 1998K. Scheffzek+2 more
semanticscholar +1 more source
GAPs galore! A survey of putative Ras superfamily GTPase activating proteins in man and Drosophila.
Biochimica et Biophysica Acta, 2003A. Bernards
semanticscholar +1 more source
Nanooncology: The future of cancer diagnosis and therapy
Ca-A Cancer Journal for Clinicians, 2013Avnesh S Thakor
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MicroRNAome genome: A treasure for cancer diagnosis and therapy
Ca-A Cancer Journal for Clinicians, 2014Ioana Berindan-neagoe+2 more
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Application of Nanotechnology in Cancer Therapy and Imaging
Ca-A Cancer Journal for Clinicians, 2008Dong M Shin
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