Despite wide sequence divergence, multiple picornaviruses use the Golgi adaptor acyl coenzyme A (acyl-CoA) binding domain protein 3 (ACBD3/GCP60) to recruit phosphatidylinositol 4-kinase class III beta (PI4KIIIβ/PI4KB), a factor required for viral ...
Alexander L. Greninger+4 more
doaj +1 more source
A Preliminary Work on Evolutionary Identification of Protein Variants and New Proteins on Grids [PDF]
Protein identification is one of the major task of Proteomics researchers. Protein identification could be resumed by searching the best match between an experimental mass spectrum and proteins from a database. Nevertheless this approach can not be used to identify new proteins or protein variants.
arxiv
Understanding Functional Protein-Protein Interactions Of ABCB11 And ADA In Human And Mouse [PDF]
Proteins are macromolecules which hardly act alone; they need to make interactions with some other proteins to do so. Numerous factors are there which can regulate the interactions between proteins [4]. Here in this present study we aim to understand Protein -Protein Interactions (PPIs) of two proteins ABCB11 and ADA from quantitative point of view ...
arxiv
Inhibition of catalytic unit of adenylate cyclase and activation of GTPase of Ni protein by βγ‐subunits of GTP‐binding proteins [PDF]
Keiichi Enomoto, Takeo Asakawa
openalex +1 more source
Scaffold proteins coordinate the assembling of multicomponent protein complexes and participate in transduction of cellular signals via multiple signaling pathways therefore acting as important regulators of cell properties.
P. A. Skovorodnikova+4 more
doaj +1 more source
HSEARCH: fast and accurate protein sequence motif search and clustering [PDF]
Protein motifs are conserved fragments occurred frequently in protein sequences. They have significant functions, such as active site of an enzyme. Search and clustering protein sequence motifs are computational intensive. Most existing methods are not fast enough to analyze large data sets for motif finding or achieve low accuracy for motif clustering.
arxiv
Protein-Tyrosine Kinases Regulate the Phosphorylation, Protein Interactions, Subcellular Distribution, and Activity of p21rasGTPase-Activating Protein [PDF]
Michael F. Moran+4 more
openalex +1 more source
Post-Translational Modification and Subcellular Distribution of Rac1: An Update
Rac1 is a small GTPase that belongs to the Rho family. The Rho family of small GTPases is a subfamily of the Ras superfamily. The Rho family of GTPases mediate a plethora of cellular effects, including regulation of cytoarchitecture, cell size, cell ...
Abdalla Abdrabou, Zhixiang Wang
doaj +1 more source
Sestrins Inhibit mTORC1 Kinase Activation through the GATOR Complex
The mechanistic target of rapamycin complex 1 (mTORC1) kinase is a sensor of different environmental conditions and regulator of cell growth, metabolism, and autophagy.
Anita Parmigiani+8 more
doaj +1 more source
Protein Hypernetworks: a Logic Framework for Interaction Dependencies and Perturbation Effects in Protein Networks [PDF]
Motivation: Protein interactions are fundamental building blocks of biochemical reaction systems underlying cellular functions. The complexity and functionality of such systems emerge not from the protein interactions themselves but from the dependencies between these interactions.
arxiv