Results 61 to 70 of about 13,809 (125)

ACBD3 Interaction with TBC1 Domain 22 Protein Is Differentially Affected by Enteroviral and Kobuviral 3A Protein Binding

open access: yesmBio, 2013
Despite wide sequence divergence, multiple picornaviruses use the Golgi adaptor acyl coenzyme A (acyl-CoA) binding domain protein 3 (ACBD3/GCP60) to recruit phosphatidylinositol 4-kinase class III beta (PI4KIIIβ/PI4KB), a factor required for viral ...
Alexander L. Greninger   +4 more
doaj   +1 more source

A Preliminary Work on Evolutionary Identification of Protein Variants and New Proteins on Grids [PDF]

open access: yesDans AINA 2006, HIPCOMB Workshop (2006), 2008
Protein identification is one of the major task of Proteomics researchers. Protein identification could be resumed by searching the best match between an experimental mass spectrum and proteins from a database. Nevertheless this approach can not be used to identify new proteins or protein variants.
arxiv  

Understanding Functional Protein-Protein Interactions Of ABCB11 And ADA In Human And Mouse [PDF]

open access: yesarXiv, 2015
Proteins are macromolecules which hardly act alone; they need to make interactions with some other proteins to do so. Numerous factors are there which can regulate the interactions between proteins [4]. Here in this present study we aim to understand Protein -Protein Interactions (PPIs) of two proteins ABCB11 and ADA from quantitative point of view ...
arxiv  

IQGAP scaffold proteins are the multifunctional regulators of cellular signaling and malignant transformation

open access: yesУспехи молекулярной онкологии, 2017
Scaffold proteins coordinate the assembling of multicomponent protein complexes and participate in transduction of cellular signals via multiple signaling pathways therefore acting as important regulators of cell properties.
P. A. Skovorodnikova   +4 more
doaj   +1 more source

HSEARCH: fast and accurate protein sequence motif search and clustering [PDF]

open access: yesarXiv, 2017
Protein motifs are conserved fragments occurred frequently in protein sequences. They have significant functions, such as active site of an enzyme. Search and clustering protein sequence motifs are computational intensive. Most existing methods are not fast enough to analyze large data sets for motif finding or achieve low accuracy for motif clustering.
arxiv  

Post-Translational Modification and Subcellular Distribution of Rac1: An Update

open access: yesCells, 2018
Rac1 is a small GTPase that belongs to the Rho family. The Rho family of small GTPases is a subfamily of the Ras superfamily. The Rho family of GTPases mediate a plethora of cellular effects, including regulation of cytoarchitecture, cell size, cell ...
Abdalla Abdrabou, Zhixiang Wang
doaj   +1 more source

Sestrins Inhibit mTORC1 Kinase Activation through the GATOR Complex

open access: yesCell Reports, 2014
The mechanistic target of rapamycin complex 1 (mTORC1) kinase is a sensor of different environmental conditions and regulator of cell growth, metabolism, and autophagy.
Anita Parmigiani   +8 more
doaj   +1 more source

Protein Hypernetworks: a Logic Framework for Interaction Dependencies and Perturbation Effects in Protein Networks [PDF]

open access: yesarXiv, 2011
Motivation: Protein interactions are fundamental building blocks of biochemical reaction systems underlying cellular functions. The complexity and functionality of such systems emerge not from the protein interactions themselves but from the dependencies between these interactions.
arxiv  

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