IQGAP Family Members in Yeast, Dictyostelium, and Mammalian Cells
International Journal of Cell Biology, 2012 IQGAPs are a family of scaffolding proteins with multiple domains, named for the IQ motifs and GTPase activating protein (GAP) related domains. Despite their GAP homology, IQGAP proteins act as effectors for GTP-bound GTPases of the Ras superfamily and ...
Katie B. Shannon
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Differential Regulation of Cellular Activities by GTPase-Activating Protein and NF1 [PDF]
, 1993 Nadia Al-Alawi +5 more
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Efficient coupling with phosphatidylinositol 3-kinase, but not phospholipase C gamma or GTPase-activating protein, distinguishes ErbB-3 signaling from that of other ErbB/EGFR family members. [PDF]
, 1994 Paolo Fedi +3 more
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Identifying Interaction Sites in "Recalcitrant" Proteins: Predicted Protein and Rna Binding Sites in Rev Proteins of Hiv-1 and Eiav Agree with Experimental Data [PDF]
arXiv, 2005 Protein-protein and protein nucleic acid interactions are vitally important for a wide range of biological processes, including regulation of gene expression, protein synthesis, and replication and assembly of many viruses. We have developed machine learning approaches for predicting which amino acids of a protein participate in its interactions with ...
arxiv
Accurate and efficient protein embedding using multi-teacher distillation learning [PDF]
arXivMotivation: Protein embedding, which represents proteins as numerical vectors, is a crucial step in various learning-based protein annotation/classification problems, including gene ontology prediction, protein-protein interaction prediction, and protein structure prediction.
arxiv
The carboxy-terminal catalytic domain of the GTPase-activating protein inhibits nuclear signal transduction and morphological transformation mediated by the CSF-1 receptor. [PDF]
, 1991 Donna M. Bortner +3 more
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Identification and partial purification of GTPase‐activating proteins from yeast and mammalian cells that preferentially act on Ypt1/Rab1 proteins [PDF]
, 1991 Tjie J. Tan +2 more
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Cdc42 mobility and membrane flows regulate fission yeast cell shape and survival
Nature CommunicationsPolarized exocytosis induced by local Cdc42 GTPase activity results in membrane flows that deplete low-mobility membrane-associated proteins. A reaction-diffusion particle model comprising Cdc42 positive feedback activation, hydrolysis by GTPase ...
David M. Rutkowski +3 more
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Specific TBC Domain-Containing Proteins Control the ER-Golgi-Plasma Membrane Trafficking of GPCRs
Cell Reports, 2019 Summary: G-protein-coupled receptors (GPCRs) constitute the largest superfamily of cell surface signaling proteins. However, the molecular mechanisms underlying their cell surface delivery after synthesis remain poorly understood. Here, we screen the TBC
Zhe Wei +10 more
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