Results 201 to 210 of about 278,687 (359)

Enhancing CHO cell recombinant protein production using a perfusion‐directed host evolution approach

Biotechnology Progress, EarlyView.
Abstract Clonally derived cell lines generated from Chinese hamster ovary (CHO) cells encounter numerous stressors when cultured in high‐intensity perfusion bioreactors leading to poor process performance. To circumvent this, the ability of CHO cells to adapt to different culture environments was exploited. Here host cells were selected in the presence
Peter Amaya, Rajesh K. Mistry, Susie Sou, Sonja Hess, Bijay Khanal, Zayla Schaeffer, Jie Zhu, Lina Chakrabarti   +7 more
wiley   +1 more source

Pan-cancer analyses identify oncogenic drivers, expression signatures, and therapeutic vulnerabilities in RHO GTPase pathway genes. [PDF]

Front Bioinform
Fernández R, Lorenzo-Martín LF, Quesada V, Bustelo XR.   +3 more
europepmc   +1 more source

Membrane identity and GTPase cascades regulated by toggle and cut‐out switches [PDF]

, 2008
Perla Del Conte‐Zerial, Lutz Brusch, Jochen C. Rink, Claudio Collinet, Yannis Kalaidzidis, Marino Zerial, Andreas Deutsch   +6 more
openalex   +1 more source

Interaction Between Actin and Microtubules During Plant Development

Cytoskeleton, EarlyView.
ABSTRACT The dynamic interaction between actin filaments (AFs) and microtubules (MTs) plays a crucial role in regulating key developmental and physiological processes in plant cells, particularly in the formation of specialized cell types with distinct shapes and functions, such as pollen tubes, trichomes, and leaf epidermal cells.
Zining Wu, Lidong Gao, M. Arif Ashraf, Qiong Nan   +3 more
wiley   +1 more source

Genetic evidence for a functional association between Parkinson's disease proteins leucine-rich repeat kinase 2 and <i>α</i>-synuclein during axonal transport. [PDF]

Front Mol Neurosci
Chakraborty P, Bajgain P, Huang J, Islam R, Banerjee R, Gunawardena S.   +5 more
europepmc   +1 more source

Coordination of cell polarization and migration by the Rho family GTPases requires Src tyrosine kinase activity [PDF]

, 2001
Paul Timpson, Gareth E. Jones, Margaret C. Frame, Valerie G. Brunton   +3 more
openalex   +1 more source

Nuclear Entanglement: New Insights Into the Role of Cytoskeleton and Nucleoskeleton in Plant Nuclear Function

Cytoskeleton, EarlyView.
ABSTRACT Of the three types of cytoskeleton known in animals—actin, microtubules, and intermediate filaments—only actin and microtubules exist in plants. Both play important roles in cellular shaping, organelle movement, organization of the endomembrane system, and cell signaling.
Norman R. Groves, Katelyn Amstutz, Lily A. Schumacher, Iris Meier   +3 more
wiley   +1 more source

Clinical and genetic characterization of <i>DNM1l</i>-related disorders: insights into genotype-phenotype correlations. [PDF]

Front Pediatr
Manting X, Hua L, Sheng H, Xiaodi H, Dan S, Fang F.   +5 more
europepmc   +1 more source

The ARF regulatory GTPase in Giardia intestinalis is associated with vesicle formation and membrane fusion machinery at non-canonical endosomal compartments [PDF]

Shweta V. Pipaliya, Emily M. Kingdon, Corina D. Wirdnam, Erina A. Balmer, Richard Kahn, Joel B. Dacks, Carmen Faso   +6 more
openalex   +1 more source

Regulation of Osteoblast Differentiation by Pasteurella Multocida Toxin (PMT): A Role for Rho GTPase in Bone Formation [PDF]

, 2004
Dympna Harmey, Gudrun Stenbeck, Catherine D. Nobes, Alistair J. Lax, Agamemnon E. Grigoriadis   +4 more
openalex   +1 more source