Regulation of intracellular cyclic GMP concentration by light and calcium in electropermeabilized rod photoreceptors. [PDF]
This study examines the regulation of cGMP by illumination and by calcium during signal transduction in vertebrate retinal photoreceptor cells. We employed an electropermeabilized rod outer segment (EP-ROS) preparation which permits perfusion of low ...
Coccia, V J, Cote, Rick H.
core +2 more sources
GTPase networks in membrane traffic.
Members of the Rab or ARF/Sar branches of the Ras GTPase superfamily regulate almost every step of intracellular membrane traffic. A rapidly growing body of evidence indicates that these GTPases do not act as lone agents but are networked to one another ...
Emi Mizuno-Yamasaki+2 more
semanticscholar +1 more source
Sbf/MTMR13 coordinates PI(3)P and Rab21 regulation in endocytic control of cellular remodeling. [PDF]
Cells rely on the coordinated regulation of lipid phosphoinositides and Rab GTPases to define membrane compartment fates along distinct trafficking routes.
Cox, Sarah+4 more
core +1 more source
Specific Rab GTPase-activating proteins define the Shiga toxin and epidermal growth factor uptake pathways [PDF]
Rab family guanosine triphosphatases (GTPases) together with their regulators define specific pathways of membrane traffic within eukaryotic cells. In this study, we have investigated which Rab GTPase-activating proteins (GAPs) can interfere with the ...
Barr, Francis A.+5 more
core +2 more sources
Rho family GTPase-dependent immunity in plants and animals
In plants, sophisticated forms of immune systems have developed to cope with a variety of pathogens. Accumulating evidence indicates that Rac (also known as Rop), a member of the Rho family of small GTPases, is a key regulator of immunity in plants and ...
Y. Kawano+2 more
semanticscholar +1 more source
Inhibition by thiostrepton of the IF‐2‐dependent ribosomal GTPase [PDF]
M. Grunberg‐Manago+2 more
openalex +1 more source
Kinetic and Structural Analysis of the Mg2+ -binding Site of the Guanine Nucleotide-binding Protein p21 H-ras. [PDF]
The coordination and binding of the Mg2+ ion in the nucleotide−binding site of p21 have been investigated using site−directed mutagenesis, kinetic methods, and phosphorous NMR.
Borasio, Gian Domenico+6 more
core
Open and cut: allosteric motion and membrane fission by dynamin superfamily proteins. [PDF]
Cells have evolved diverse protein-based machinery to reshape, cut, or fuse their membrane-delimited compartments. Dynamin superfamily proteins are principal components of this machinery and use their ability to hydrolyze GTP and to polymerize into ...
Frost, Adam, Kalia, Raghav
core
Studies of the GTPase domain of archaebacterial ribosomes [PDF]
Alan A. D. BEAUCLERK+4 more
openalex +1 more source
The Iron-Type Nitrile Hydratase Activator Protein Is A GTPase [PDF]
The Fe-type nitrile hydratase activator protein from Rhodococcus equi TG328-2 (ReNHase TG328-2) was successfully expressed and purified. Sequence analysis and homology modeling suggest that it is a G3E P-loop guanosine triphosphatase (GTPase) within the ...
Bennett, Brian+3 more
core +1 more source