Results 31 to 40 of about 4,383 (215)
Evidence that resistin acts on the mechanical responses of the mouse gastric fundus
Frontiers in Physiology, 2022 Resistin, among its several actions, has been reported to exert central anorexigenic effects in rodents. Some adipokines which centrally modulate food intake have also been reported to affect the activity of gastric smooth muscle, whose motor responses ...
Eglantina Idrizaj +4 more
doaj +1 more source
Glucocorticoid treatment in patients with complex regional pain syndrome: A systematic review
European Journal of Pain, Volume 26, Issue 10, Page 2009-2035, November 2022., 2022 Abstract Background and objective The pathophysiology of complex regional pain syndrome (CRPS) is multifactorial, with an exaggerated inflammatory response being the most prominent. Treatment for CRPS is carried out according to the presenting pathophysiological mechanism. Anti‐inflammatory treatment with glucocorticoids is therefore an option. The aim
Corinne van den Berg +3 more
wiley +1 more source
Physiological Reports, Volume 10, Issue 21, November 2022., 2022 Role of Acetylcholine in steroid biosynthesis and follicular development in the rat ovary. The follicles of the rat ovary do not receive a direct extraovarian cholinergic innervation. It mainly originated from an intraovarian source of Acetylcholine (a).
Fernanda C. Cuevas +8 more
wiley +1 more source
The Pressor Action of Guanethidine in the Spinal Cat [PDF]
, 1962 Guanethidine has a marked pressor action in the spinal cat. Doses of 2–4 mg./kg. produce a greater increase in blood pressure than doses of 8–16 mg./kg.
A L Bartlet
core +1 more source
Reproductive Biology and Endocrinology, 2018 Background The injection of estradiol valerate in female rats induces polycystic ovary syndrome, which is characterized by polycystic ovaries, anovulation, and hyperandrogenism.
Julieta A. Espinoza +4 more
doaj +1 more source
Antihypertensive and noradrenaline-depleting effects of guanethidine metabolites [PDF]
, 1971 The antihypertensive and myocardial noradrenaline-depleting activities of the three identified guanethidine metabolites were compared with those of guanethidine itself.
H BRUNNER, L MAÎTRE, M STAEHELIN
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Effects of Guanethidine and Related Compounds on Histamine Excretion [PDF]
, 1972 The basic nature of guanethidine and some of its effects suggested a possible action of this drug on histamine metabolism. A single intraperitoneal injection of guanethidine (10 mg/kg) in male rats was found to double the daily urinary excretion of free
J. Côté +3 more
core +1 more source
Antagonism of Guanethidine by Dexamphetamine and Other Related Sympathomimetic Amines [PDF]
, 1962 Dexamphetamine and certain other indirectly acting sympathomimetic amines prevent or reverse the sympathetic nerve blocking action of guanethidine in anaesthetised cats and dogs.
M D Day, M J Rand
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Virtual Screen for Repurposing of Drugs for Candidate Influenza a M2 Ion-Channel Inhibitors
Frontiers in Cellular and Infection Microbiology, 2019 Influenza A virus (IAV) matrix protein 2 (M2), an ion channel, is crucial for virus infection, and therefore, an important anti-influenza drug target.
Draginja Radosevic +10 more
doaj +1 more source
Guanethidine N-oxidation in human liver microsomes [PDF]
, 1987 The capacity of human liver microsomes to N-oxidize guanethidine from 25 subjects has been assessed. Guanethidine N-oxidation was optimal at pH 8ṁ5 and proceeded at only 16% of the maximal rate at pH 7ṁ4.
P H Grantham +4 more
core +1 more source