Results 41 to 50 of about 4,383 (215)

Sympathetic Fibre Sprouting in the Skin Contributes to Pain-Related Behaviour in Spared Nerve Injury and Cuff Models of Neuropathic Pain

open access: yesMolecular Pain, 2015
Background Cuff and spared nerve injury (SNI) in the sciatic territory are widely used to model neuropathic pain. Because nociceptive information is first detected in skin, it is important to understand how alterations in peripheral innervation ...
Francisney P. Nascimento   +3 more
doaj   +1 more source

Effects of Guanethidine and Imidazole on Histamine Response [PDF]

open access: yes, 1974
Guanethidine was shown to increase sensitivity (as measured by blood pressure response) not only to noradrenaline but to acetylcholine and histamine (H) as well.
J. Côté, J. LeBlanc, F. Doré
core   +1 more source

Vasodilator Action of Guanethidine [PDF]

open access: yesCirculation Research, 1962
The cardiovascular effects of intravenous guanethidine were measured in animals treated with reserpine. The action of intraarterial guanethidine was studied also in perfused forelegs of dogs. The following conclusions were reached: 1. There was no significant increase in cardiac output, heart rate, or systemic arterial pressure following ...
F M, ABBOUD, J W, ECKSTEIN
openaire   +2 more sources

The effect of guanethidine and local anaesthetics on the electrically stimulated mouse vas deferens [PDF]

open access: yes, 2002
Complex regional pain syndrome is often treated with the sympatholytic guanethidine and a local anesthetic in a Bier's block. The efficacy of this treatment has been questioned.
JOYCE PI   +5 more
core   +1 more source

Effect of neuronal uptake inhibitors on the adrenergic-neuron blockade produced by guanethidine in rabbit vas deferens [PDF]

open access: yes, 1977
The effect of neuronal-uptake inhibitors on the guanethidine-induced inhibition of responses of rabbit vas deferens to transmural stimulation was investigated.
D. M. Paton, L. J. Huston, D. S. Golko
core   +1 more source

Tumor necrosis factor, interleukin-1 and interleukin-8 mediate the nociceptive activity of the supernatant of LPS-stimulated macrophages

open access: yesMediators of Inflammation, 1997
It has been suggested that the supernatant of LPSstimulated macrophages (macrophage nociceptive factor, MNF) promotes nociception in mice. Intraperitoneal administration of MNF induced dose-related writhing, which reached a plateau between 18 and 26 min ...
S. M. Thomazzi   +4 more
doaj   +1 more source

A calcium requirement for release of 3H-guanethidine by sympathetic nerve stimulation [PDF]

open access: yes, 1966
Cat colons were labelled with 3H-guanethidine by close intra-arterial injection. Two hr later the colons were removed and the vascular bed was perfused with Krebs solution containing 0, 2·5 or 5 mM calcium.
D J BOULLIN
core   +1 more source

Subcellular distribution of [3H]amphetamine and [3H]guanethidine and their interaction with adrenergic neurons [PDF]

open access: yes, 1968
The subcellular distribution of [3H]amphetamine and [3H]guanethidine and their interaction with each other and with noradrenaline binding sites have been examined.
R Stitzel, H O Obianwu, P Lundborg
core   +1 more source

Adrenergic Stimulation–Released Histamine Taken-up in Adrenergic Nerves Induces Endothelium-Dependent Vasodilation in Rat Mesenteric Resistance Arteries

open access: yesJournal of Pharmacological Sciences, 2012
The present study investigated whether histamine was taken up by perivascular adrenergic nerves and released by periarterial nerve stimulation (PNS) to induce vascular responses.
Yuto Haruki   +6 more
doaj   +1 more source

Anti-asialo GM1 antibodies prevents guanethidine-induced sympathectomy in athymic rats [PDF]

open access: yes, 1992
Guanethidine sulphate induces destruction of peripheral sympathetic neurons and infiltration of mononuclear cells in rat sympathetic ganglia. The effect of guanethidine is believed to be an autoimmune reaction.
H.B. Christensen   +11 more
core   +1 more source

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